{"id":"W2121763480","doi":"10.4049/jimmunol.174.12.7548","title":"A Defective Viral Superantigen-Presenting Phenotype in HLA-DR Transfectants Is Corrected by CIITA","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Saint-Luc; Université de Montréal","funders":"","keywords":"CIITA; Biology; Cell biology; Transfection; Antigen presentation; MHC class II; Endocytic cycle; Major histocompatibility complex; Antigen processing; MHC class I; T cell; Cytoplasm; HeLa; Molecular biology; Antigen; Cell culture; Cell; Immunology; Immune system; Genetics; Endocytosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003071484,0.0009011084,0.0005306876,0.0005801315,0.0002387708,0.0006399478,0.0006581838,0.0005231605,0.002267367],"category_scores_gemma":[0.0003002397,0.0003527243,0.0004021847,0.0003228345,0.0003775503,0.0002239419,0.0003667958,0.001314562,0.001495716],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004886218,"about_ca_system_score_gemma":0.0003307614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008915315,"about_ca_topic_score_gemma":0.0006912256,"domain_scores_codex":[0.9994441,0.00009725941,0.0001032886,0.000113033,0.0001263283,0.000116035],"domain_scores_gemma":[0.9992092,0.0001746931,0.0002168843,0.0001565322,0.00005431781,0.000188377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005870794,0.00001944244,0.000048951,0.00001566927,0.00000379412,0.00004901809,0.00002046658,0.00002880429,0.999155,0.0001459802,0.00002362799,0.0004304766],"study_design_scores_gemma":[0.000012332,0.00009961159,0.001117791,0.000005487794,0.000008841133,0.0002562309,0.00002065212,0.0007392071,0.9955482,0.00002288948,0.002164075,0.000004706043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98694,0.001099705,0.007042684,0.0001564561,0.0001076097,0.00007849264,0.0008971186,0.0007337763,0.002944094],"genre_scores_gemma":[0.9814441,0.0007835174,0.006024255,0.00005870594,0.00002704931,0.0001301343,0.002151274,0.0004296049,0.008951361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002267367,"threshold_uncertainty_score":0.007585049,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008860763105302802,"score_gpt":0.2412882068042758,"score_spread":0.2324274436989731,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}