{"id":"W2121835375","doi":"10.1002/anie.200904747","title":"Activation of Allylic CF bonds: Palladium‐Catalyzed Allylic Amination of 3,3‐Difluoropropenes","year":2009,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Fluorine in Organic Chemistry","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":146,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Allylic rearrangement; Palladium; Amination; Catalysis; Chemistry; Combinatorial chemistry; Medicinal chemistry; Stereochemistry; Computer science; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003562267,0.0002012222,0.0002573168,0.0001433863,0.00005428417,0.00001287632,0.0003754467,0.0002972182,0.001842412],"category_scores_gemma":[0.0003913291,0.0002122587,0.0001065876,0.0002147895,0.0001321398,0.0003529987,0.00005466418,0.0003167065,0.00002266267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000182592,"about_ca_system_score_gemma":0.00008162211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002653713,"about_ca_topic_score_gemma":0.000003090246,"domain_scores_codex":[0.9984661,0.00004551121,0.0005830326,0.0002916683,0.0004157264,0.0001979181],"domain_scores_gemma":[0.9984587,0.0001994041,0.0005059335,0.0002043524,0.0005480599,0.00008355936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002591772,0.0004288835,0.0006208937,0.00005970851,0.0001353658,0.000003646504,0.0002513352,0.00006994182,0.9837613,0.0006577531,0.007362091,0.006389875],"study_design_scores_gemma":[0.001316725,0.00009271705,0.00473744,0.00006524262,0.00006898419,0.0000159331,0.0000670297,0.0002454503,0.9824523,0.001219255,0.009539142,0.0001798244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9749163,0.0001359845,0.0008876747,0.003678175,0.001141065,0.0002828843,0.0001482672,0.00009160671,0.01871798],"genre_scores_gemma":[0.996191,0.0001818354,0.0002902157,0.0004087813,0.001010612,0.00002156958,0.001080411,0.00001838571,0.0007971749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02127465,"threshold_uncertainty_score":0.99907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05104543215406002,"score_gpt":0.374391386105952,"score_spread":0.323345953951892,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}