{"id":"W2121858345","doi":"10.1016/j.gene.2011.06.014","title":"Transcriptional regulation of antioxidant enzymes by FoxO1 under dehydration stress","year":2011,"lang":"en","type":"article","venue":"Gene","topic":"FOXO transcription factor regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto","keywords":"Biology; FOXO1; Catalase; Superoxide dismutase; Oxidative stress; Transcription factor; Antioxidant; Molecular biology; Gene expression; Biochemistry; Internal medicine; Endocrinology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001446464,0.0002820943,0.0003175721,0.0002028566,0.0003372834,0.0003258618,0.0001710886,0.0002058721,0.00212293],"category_scores_gemma":[0.0001400572,0.0001646903,0.0003158157,0.0001669179,0.000414552,0.0004079877,0.0003764333,0.0005421315,0.0002634412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006141432,"about_ca_system_score_gemma":0.0002445266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001597817,"about_ca_topic_score_gemma":0.002778082,"domain_scores_codex":[0.9998914,0.00000958107,0.000004996163,0.00003824848,0.0000138444,0.00004193509],"domain_scores_gemma":[0.9999026,0.00001204194,0.00002339615,0.00001122781,0.00001691954,0.00003380222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000319069,0.00001530678,0.000460147,0.00002731622,0.000004793962,0.00002825511,0.00002839466,0.00003235136,0.9978558,0.000184091,0.00008579859,0.00095871],"study_design_scores_gemma":[0.00005699226,0.0001722756,0.05084979,0.00001612832,0.00003757271,0.0001772672,0.0001792458,0.001346174,0.9437875,0.00049589,0.002863006,0.00001818385],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921187,0.001871052,0.002957469,0.0004271519,0.00009122703,0.00001738442,0.0006611805,0.0000905121,0.001765346],"genre_scores_gemma":[0.9929588,0.0004977897,0.001160363,0.0001303257,0.00002135325,0.0000181396,0.0007826255,0.00002664643,0.004403963],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00212293,"threshold_uncertainty_score":0.007101953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01842593157947038,"score_gpt":0.2141102034776632,"score_spread":0.1956842718981928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}