{"id":"W2121858345","doi":"10.1016/j.gene.2011.06.014","title":"Transcriptional regulation of antioxidant enzymes by FoxO1 under dehydration stress","year":2011,"lang":"en","type":"article","venue":"Gene","topic":"FOXO transcription factor regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto","keywords":"Biology; FOXO1; Catalase; Superoxide dismutase; Oxidative stress; Transcription factor; Antioxidant; Molecular biology; Gene expression; Biochemistry; Internal medicine; Endocrinology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007972957,0.0001064179,0.00009004185,0.00004303501,0.00004127395,0.000006567296,0.00008245913,0.0001206402,0.0001640352],"category_scores_gemma":[0.000005453693,0.0001106135,0.00007328384,0.0000649939,0.00006387835,0.0000121938,0.000008315953,0.000031568,0.000005223603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000110841,"about_ca_system_score_gemma":0.00002772772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002981546,"about_ca_topic_score_gemma":0.00003841426,"domain_scores_codex":[0.9992371,0.00004295722,0.0002280057,0.0002157443,0.0001570855,0.0001191642],"domain_scores_gemma":[0.9995781,0.00000235894,0.00008846705,0.0001934282,0.00009737606,0.00004025352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007993713,0.00008412591,0.001566751,0.00001171026,0.00003295059,8.971737e-8,0.00009378276,0.0001970904,0.9953306,0.001608921,0.0004521944,0.000541826],"study_design_scores_gemma":[0.0003572,0.0001081768,0.1179043,0.000006235736,0.00001682524,0.000002709013,0.00002864311,0.00009233672,0.8798522,0.0003516412,0.001174437,0.000105279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.930656,0.000725701,0.06768922,0.00004202215,0.0001391177,0.0001353533,0.0001051576,0.00001511036,0.0004922791],"genre_scores_gemma":[0.9968601,0.00005426113,0.001758797,0.00004246438,0.00006285203,0.000009046989,0.0007917879,0.00001557039,0.000405147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1163375,"threshold_uncertainty_score":0.4510686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01842593157947038,"score_gpt":0.2141102034776632,"score_spread":0.1956842718981928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}