{"id":"W2121858612","doi":"10.1101/gad.2050411","title":"Sweet DREAMs for Hippo","year":2011,"lang":"en","type":"letter","venue":"Genes & Development","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Cancer Care Ontario","funders":"Canadian Institutes of Health Research","keywords":"Biology; Hippo signaling pathway; Cell biology; Cell growth; Cell cycle; Retinoblastoma; Cell cycle progression; Gene; Retinoblastoma protein; Signal transduction; Cancer research; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002441058,0.0004574999,0.0003414221,0.00008350651,0.0001622912,0.00003474227,0.0004610324,0.001029882,0.00008105347],"category_scores_gemma":[0.00002345302,0.0004354724,0.0002028587,0.00004976472,0.00005156636,0.000001494659,0.0001551208,0.0002843815,0.0001510182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003915007,"about_ca_system_score_gemma":0.0005740367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009834494,"about_ca_topic_score_gemma":0.00001281474,"domain_scores_codex":[0.9979432,0.00004712053,0.0004086746,0.0007623942,0.0002184452,0.0006201585],"domain_scores_gemma":[0.9990414,0.00001514344,0.0001702216,0.0005284271,0.0001563274,0.00008846468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004690608,0.0000389556,0.00008834307,0.0002147779,0.0003599602,0.00003799058,0.0002485427,0.000003076719,0.1448428,0.000006195877,0.8202454,0.03386696],"study_design_scores_gemma":[0.000232735,0.00009354637,0.00003436247,0.0000344424,0.00003265,0.00001401158,0.000008574752,6.60894e-7,0.2559821,0.0000634611,0.7430209,0.0004825306],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.5515152,0.06214114,0.08056585,0.2396264,0.02356187,0.01223694,0.002129786,0.001047709,0.0271751],"genre_scores_gemma":[0.01131303,0.001582244,0.08280613,0.7375163,0.02387461,0.002720112,0.03332509,0.0007932304,0.1060692],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.5402022,"threshold_uncertainty_score":0.9998097,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02629368942476236,"score_gpt":0.2375504836066506,"score_spread":0.2112567941818883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}