{"id":"W2121900331","doi":"10.1016/j.jaci.2010.09.021","title":"Innate signals from Nod2 block respiratory tolerance and program TH2-driven allergic inflammation","year":2010,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":91,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health","keywords":"Thymic stromal lymphopoietin; Immunology; NOD2; Pattern recognition receptor; Innate immune system; Acquired immune system; Immune tolerance; Innate lymphoid cell; Allergic inflammation; Inflammation; Biology; Medicine; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009794934,0.000215583,0.0006019003,0.000160637,0.0001868596,0.00003801376,0.0002718259,0.0008381562,0.0002624859],"category_scores_gemma":[0.0006453231,0.0001748908,0.0001675636,0.00008803086,0.0006940732,0.0003167321,0.0001330333,0.001469329,0.00006592671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000107327,"about_ca_system_score_gemma":0.0001263067,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000232113,"about_ca_topic_score_gemma":0.0001029732,"domain_scores_codex":[0.9973547,0.0006361857,0.001401277,0.0002557554,0.00006037495,0.0002917132],"domain_scores_gemma":[0.9975426,0.0009098065,0.0009402057,0.000258948,0.0002983457,0.00005009735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002535305,0.0002778327,0.002865649,0.000006034468,0.002154477,0.00003732981,0.0004064601,0.00001518908,0.8516015,0.0007108877,0.0004577647,0.1389316],"study_design_scores_gemma":[0.01021966,0.004800769,0.3607225,0.0002034063,0.0002225827,0.0004819467,0.0003766342,0.0001237333,0.08700948,0.00192547,0.533326,0.0005877771],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882129,0.008528743,0.00002698231,0.001154341,0.001659677,0.0001700287,0.000002857424,0.00003338489,0.0002111197],"genre_scores_gemma":[0.9922978,0.006453164,0.0004088597,0.0002672203,0.0003198056,0.000008780808,0.00001466442,0.00001753395,0.000212171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.764592,"threshold_uncertainty_score":0.7131842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01739700461109248,"score_gpt":0.3011756002064367,"score_spread":0.2837785955953442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}