{"id":"W2121912512","doi":"10.1101/gad.254870.114","title":"A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation","year":2015,"lang":"en","type":"article","venue":"Genes & Development","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Methyltransferase; Methylation; Histone methyltransferase; Histone H3; Protein subunit; Phosphorylation; Transferase; Histone; Biochemistry; Cell biology; Enzyme; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005651017,0.0001739661,0.0001116229,0.00007947557,0.00009823485,0.0001561047,0.0001678722,0.0001037107,0.002383403],"category_scores_gemma":[0.00009392387,0.00009772481,0.0001237901,0.00005977969,0.0001530321,0.000116871,0.0001757501,0.0001641811,0.0004557084],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002347546,"about_ca_system_score_gemma":0.0001079649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006812626,"about_ca_topic_score_gemma":0.001074989,"domain_scores_codex":[0.9999548,0.000006110003,0.000002541811,0.00001372754,0.000007585082,0.00001518117],"domain_scores_gemma":[0.9999582,0.000005925399,0.00001123619,0.000005043451,0.000003007145,0.0000166476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001681243,0.000008557651,0.0002188071,0.00001009474,0.000002074148,0.00002382247,0.000006250525,0.00005807145,0.9984185,0.0001069697,0.00002146706,0.0009573529],"study_design_scores_gemma":[0.0000271089,0.0001377613,0.008589434,0.000003109949,0.000008596727,0.00008942477,0.00002452088,0.001501325,0.988414,0.0000695635,0.001129871,0.000005395745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973029,0.000347079,0.00102924,0.00003689207,0.00001341048,0.00000421712,0.00006576372,0.00005654846,0.001143978],"genre_scores_gemma":[0.9989678,0.00009963815,0.0003041954,0.00001262185,0.000002084777,0.000002009506,0.00005018604,0.00000873098,0.0005527184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002383403,"threshold_uncertainty_score":0.007973313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02637665844455659,"score_gpt":0.2836060950034979,"score_spread":0.2572294365589413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}