{"id":"W2121921260","doi":"10.1128/cdli.9.6.1212-1221.2002","title":"Nef Protein of Human Immunodeficiency Virus and Lipopolysaccharide Induce Expression of CD14 on Human Monocytes through Differential Utilization of Interleukin-10","year":2002,"lang":"en","type":"article","venue":"Clinical and Vaccine Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Ottawa","funders":"Canadian Foundation for AIDS Research; amfAR, The Foundation for AIDS Research","keywords":"CD14; Lipopolysaccharide; Biology; Peripheral blood mononuclear cell; Monocyte; Cytokine; Downregulation and upregulation; Interleukin; Immunology; Virology; Molecular biology; In vitro; Immune system; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001423932,0.0002336884,0.0001676228,0.0002050546,0.0001036082,0.0002051449,0.00007518093,0.0002158327,0.0009842644],"category_scores_gemma":[0.0001724742,0.0001189962,0.0002429881,0.0001025046,0.0000831673,0.00009709947,0.0002051708,0.0002294188,0.0002817078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001238304,"about_ca_system_score_gemma":0.0001096576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003121375,"about_ca_topic_score_gemma":0.0004526948,"domain_scores_codex":[0.9998148,0.00004828935,0.00001875109,0.00001985773,0.00003426224,0.00006416968],"domain_scores_gemma":[0.9999136,0.00002608206,0.00001278813,0.00001068592,0.00001648835,0.00002043985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004697072,0.00006483164,0.001447239,0.00004680451,0.000005648677,0.0001929016,0.0000442148,0.00002648038,0.9947307,0.00008147996,0.00002651925,0.002863384],"study_design_scores_gemma":[0.00009908633,0.001662346,0.04381357,0.0000270361,0.00003179658,0.001018134,0.000140807,0.001356686,0.9475666,0.0001117626,0.00416229,0.000009918082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961393,0.001530283,0.001155926,0.00003276639,0.00002421505,0.00004733703,0.0001058866,0.000008420452,0.0009558559],"genre_scores_gemma":[0.9940109,0.0007741979,0.00308335,0.00005486036,0.00001421454,0.00007375189,0.0003446343,0.000003540442,0.001640563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009842644,"threshold_uncertainty_score":0.00329262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1172562745645299,"score_gpt":0.3792661819130627,"score_spread":0.2620099073485328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}