{"id":"W2121922160","doi":"10.1002/cbic.200800538","title":"The Molecular Basis of Inhibition of Golgi α‐Mannosidase II by Mannostatin A","year":2008,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"National Center for Research Resources; National Institute of General Medical Sciences","keywords":"Mannosidase; Chemistry; Golgi apparatus; Mannose; Stereochemistry; Cleavage (geology); Enzyme; Glycan; Binding site; Active site; Biochemistry; Biology; Cell; Glycoprotein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000105268,0.0001857401,0.0002554279,0.0000179384,0.0001628617,0.000006886971,0.0002135667,0.0001525209,0.0002696446],"category_scores_gemma":[0.0001952266,0.0001613663,0.0001906032,0.0001782758,0.0003333385,0.00003991394,0.0001032033,0.000136311,0.000004491703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003708529,"about_ca_system_score_gemma":0.00004758636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002558309,"about_ca_topic_score_gemma":5.436396e-7,"domain_scores_codex":[0.9988075,0.00001176397,0.0004225183,0.0002515287,0.00027671,0.0002299851],"domain_scores_gemma":[0.9988856,0.0001331372,0.0002530859,0.0005184883,0.0001327476,0.00007696127],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004805463,0.000153257,0.00008531314,0.0001948989,0.00005344706,0.00001460315,0.0002913108,0.000001078654,0.9923114,0.00007898423,0.006309679,0.000457931],"study_design_scores_gemma":[0.000370469,0.00001459269,0.00001190183,0.000076282,0.00003316311,0.00001748752,0.0002944059,0.00002130896,0.9968111,0.00009373138,0.002092881,0.0001626847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9763523,0.001086824,0.0000129618,0.0002245909,0.00001524707,0.00004546025,0.0001261791,0.00003108922,0.0221053],"genre_scores_gemma":[0.9974878,0.0001439976,0.00007753394,0.00002747502,0.00003059658,0.00002573079,0.0001014621,0.00002341922,0.002081987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02113545,"threshold_uncertainty_score":0.6580328,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007087049451231695,"score_gpt":0.1948085810941563,"score_spread":0.1877215316429246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}