{"id":"W2121935084","doi":"10.1001/jama.292.11.1317","title":"Surveillance of <EMPH TYPE=\"ITAL\">BRCA1</EMPH> and <EMPH TYPE=\"ITAL\">BRCA2</EMPH> Mutation Carriers With Magnetic Resonance Imaging, Ultrasound, Mammography, and Clinical Breast Examination","year":2004,"lang":"en","type":"article","venue":"JAMA","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1167,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Medicine; Mammography; Breast cancer; Magnetic resonance imaging; Ultrasound; Radiology; Malignancy; Breast MRI; Gynecology; Cancer; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005128014,0.0002274247,0.0001949538,0.0006856024,0.0005326249,0.0002652131,0.0004255301,0.0002284825,0.00129481],"category_scores_gemma":[0.001652606,0.0001227926,0.0001605725,0.0006420048,0.0004154593,0.0001783623,0.0001943023,0.0001920945,0.0001692207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002018564,"about_ca_system_score_gemma":0.002458399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.3270794,"about_ca_topic_score_gemma":0.5132188,"domain_scores_codex":[0.9997085,0.00003741413,0.00001843675,0.00005073915,0.0001088923,0.00007595058],"domain_scores_gemma":[0.9992812,0.00008831643,0.0003205363,0.00001878561,0.0001511172,0.0001399494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001301301,0.00003138552,0.9942514,0.00002403758,0.000015347,0.000114674,0.00005353811,0.00003167234,0.0004488208,0.00000618812,0.0002928315,0.004599995],"study_design_scores_gemma":[0.00001322432,0.0001234523,0.9984817,0.0000181118,0.00001976007,0.0005480536,0.0001376196,0.00009790654,0.000239404,0.000008238942,0.0003094735,0.000003132776],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982536,0.0003763091,0.00005021037,0.00009396191,0.000003503522,0.00004051934,0.0005282954,0.00000618522,0.0006475098],"genre_scores_gemma":[0.9980951,0.0005059624,0.0003340208,0.00006148193,0.00001174903,0.00001737291,0.0007193846,0.000001843242,0.0002531096],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3270794,"threshold_uncertainty_score":0.6503512,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006063549907399052,"score_gpt":0.2449691126916466,"score_spread":0.2389055627842476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}