{"id":"W2121939895","doi":"10.1038/labinvest.2009.13","title":"Mitochondrial control of platelet apoptosis: effect of cyclosporin A, an inhibitor of the mitochondrial permeability transition pore","year":2009,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Heart and Stroke Foundation of Canada","keywords":"MPTP; Apoptosis; Platelet; Mitochondrial permeability transition pore; Phosphatidylserine; Platelet activation; Biology; Cell biology; Immunology; Programmed cell death; Biochemistry; Endocrinology; Membrane; Phospholipid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004091386,0.0003046842,0.0003083025,0.0003302661,0.0003816145,0.0008080443,0.0003590577,0.0004216681,0.0007388308],"category_scores_gemma":[0.0005337997,0.0001257265,0.0003034434,0.0003170617,0.0006356403,0.0004901402,0.0002291802,0.001428282,0.0001377091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008689898,"about_ca_system_score_gemma":0.0007094142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008955917,"about_ca_topic_score_gemma":0.0008450767,"domain_scores_codex":[0.9997661,0.00006762522,0.00002018719,0.00002910295,0.00005394804,0.00006309716],"domain_scores_gemma":[0.9995796,0.0001154326,0.0001014121,0.00006059623,0.00004467386,0.00009833206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007699476,0.000474796,0.0006531148,0.0001700601,0.00005047489,0.0005062813,0.0001112702,0.0004746475,0.9768489,0.002137703,0.0004242256,0.01044901],"study_design_scores_gemma":[0.0006341809,0.002319774,0.006438293,0.00001507709,0.00009154439,0.0009087774,0.0001207156,0.00300206,0.982949,0.0004661596,0.003041071,0.00001343349],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895462,0.005623209,0.001659235,0.0007189767,0.0001004313,0.00002791686,0.0001348469,0.00008082033,0.002108362],"genre_scores_gemma":[0.9970338,0.001681077,0.0005658806,0.00004165842,0.00005364178,0.00001495143,0.00007736124,0.000007688444,0.0005239348],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008955917,"threshold_uncertainty_score":0.006304979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003747400039549189,"score_gpt":0.2088086687151133,"score_spread":0.2050612686755642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}