{"id":"W2121980868","doi":"10.1128/aem.03015-10","title":"Molecular Basis for Mycophenolic Acid Biosynthesis in Penicillium brevicompactum","year":2011,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fondation Chalmers; Danmarks Frie Forskningsfond","keywords":"Penicillium; Mycophenolic acid; Biosynthesis; Biology; Chemistry; Computational biology; Biochemistry; Microbiology; Genetics; Enzyme; Medicine; Transplantation","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000112824,0.0003625873,0.000297208,0.0003289871,0.0002194743,0.0004355334,0.0002213453,0.0004109917,0.0004885785],"category_scores_gemma":[0.0003092539,0.0001892046,0.0003295389,0.0003070731,0.0002521711,0.0002410197,0.0002715137,0.0006780169,0.0004871805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003619636,"about_ca_system_score_gemma":0.0003748682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009124124,"about_ca_topic_score_gemma":0.0004999366,"domain_scores_codex":[0.9998751,0.00002037399,0.00001349336,0.00003052624,0.00004181971,0.00001875231],"domain_scores_gemma":[0.9998198,0.00004246223,0.00004327161,0.00003065056,0.00003078732,0.00003303438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000438591,0.00001046694,0.0003580907,0.00003138711,0.000002577204,0.0001323987,0.00001188832,0.0001604685,0.997781,0.0001327651,0.00001407877,0.001320997],"study_design_scores_gemma":[0.0000211892,0.00020481,0.02183794,0.00002034654,0.00003033809,0.001076826,0.00009951244,0.002768082,0.9697697,0.0005472041,0.003608993,0.00001513299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871181,0.001781916,0.0081755,0.0005416481,0.0000254589,0.00004138557,0.0008523418,0.0001153743,0.001348358],"genre_scores_gemma":[0.9870929,0.0009169545,0.008066776,0.000104278,0.00001345749,0.00003493477,0.002706189,0.0000253711,0.00103917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009124124,"threshold_uncertainty_score":0.00262624,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01047737438106367,"score_gpt":0.201271528006253,"score_spread":0.1907941536251893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}