{"id":"W2122009299","doi":"10.1074/jbc.m109.071993","title":"Phospholipase C Activity Affinity Purifies with the Torpedo Nicotinic Acetylcholine Receptor","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Phosphatidic acid; Alpha-4 beta-2 nicotinic receptor; Muscarinic acetylcholine receptor M5; Chemistry; Acetylcholine; Diacylglycerol kinase; Nicotinic agonist; Biochemistry; Acetylcholine receptor; Muscarinic acetylcholine receptor M3; Nicotinic acetylcholine receptor; Phosphatidate; Phospholipase D; Receptor; Biology; Phospholipid; Signal transduction; Endocrinology; Protein kinase C; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002172275,0.0009091378,0.0003674554,0.0002799589,0.0002369875,0.000432231,0.0003061208,0.0002717755,0.001341727],"category_scores_gemma":[0.0003912005,0.0001799389,0.0003751874,0.0002915462,0.0002529689,0.000257038,0.0004138661,0.0006700653,0.0008852797],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000522904,"about_ca_system_score_gemma":0.0003360409,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001791397,"about_ca_topic_score_gemma":0.001733923,"domain_scores_codex":[0.9997192,0.0000356085,0.00003046779,0.00005361276,0.00009346101,0.00006765017],"domain_scores_gemma":[0.9998453,0.00003637498,0.00002870465,0.00002528062,0.00003809147,0.00002614104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007241318,0.0000242032,0.0002317222,0.00004969367,0.00001199817,0.00006066814,0.000008997396,0.00004715495,0.9973265,0.0000910881,0.00006627185,0.002009349],"study_design_scores_gemma":[0.0000237916,0.0001642527,0.005848256,0.00001547021,0.00003979164,0.0006428976,0.00002119302,0.0009954083,0.9844358,0.00006507908,0.00773572,0.00001222125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9535663,0.00752092,0.02880097,0.000708645,0.0001692408,0.0003226596,0.001335163,0.0002323172,0.007343918],"genre_scores_gemma":[0.953815,0.00627086,0.02253293,0.0003562634,0.00007500757,0.0002578644,0.006078073,0.00007655497,0.01053747],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001791397,"threshold_uncertainty_score":0.004488528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01198294254866442,"score_gpt":0.2520699698400269,"score_spread":0.2400870272913625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}