{"id":"W2122009299","doi":"10.1074/jbc.m109.071993","title":"Phospholipase C Activity Affinity Purifies with the Torpedo Nicotinic Acetylcholine Receptor","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Phosphatidic acid; Alpha-4 beta-2 nicotinic receptor; Muscarinic acetylcholine receptor M5; Chemistry; Acetylcholine; Diacylglycerol kinase; Nicotinic agonist; Biochemistry; Acetylcholine receptor; Muscarinic acetylcholine receptor M3; Nicotinic acetylcholine receptor; Phosphatidate; Phospholipase D; Receptor; Biology; Phospholipid; Signal transduction; Endocrinology; Protein kinase C; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008410822,0.000313331,0.0003963204,0.00001508439,0.0001568798,0.00004607952,0.0007901972,0.0004517206,0.0004220967],"category_scores_gemma":[0.0008334353,0.0001645647,0.0002841736,0.0001503527,0.0004728812,0.00001138181,0.0002531667,0.001271831,0.00001303345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002109727,"about_ca_system_score_gemma":0.0002035278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003755112,"about_ca_topic_score_gemma":0.00001371735,"domain_scores_codex":[0.9984407,0.0001026146,0.0004227611,0.0003574807,0.0002949862,0.0003814859],"domain_scores_gemma":[0.9981489,0.0001198194,0.0006338492,0.0005492546,0.0003233724,0.0002248016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006860018,0.000361513,0.005723743,0.000009478242,0.0001154912,0.000001962105,0.00002238147,0.000005876332,0.9847259,0.000003527025,0.007099286,0.001244824],"study_design_scores_gemma":[0.001015674,0.0005124603,0.001607639,0.00001126871,0.00003410067,0.0002449205,0.000127394,0.000001825237,0.9116248,0.000007426454,0.08457935,0.0002330743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966677,0.0003669962,0.0001120999,0.001457273,0.0003208043,0.0001418621,0.00001942093,0.00001551253,0.0008983549],"genre_scores_gemma":[0.9959682,0.0003396845,0.0009949895,0.0002340178,0.001794543,0.00001042923,0.00001744169,0.00002425434,0.0006164844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07748006,"threshold_uncertainty_score":0.6710753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01198294254866442,"score_gpt":0.2520699698400269,"score_spread":0.2400870272913625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}