{"id":"W2122015259","doi":"10.1002/bit.23253","title":"Endothelial nanoparticle binding kinetics are matrix and size dependent","year":2011,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"3D Printing in Biomedical Research","field":"Engineering","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; Foothills Medical Centre; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Internalization; Nanoparticle; Endocytosis; Biophysics; Umbilical vein; Nanotechnology; Particle size; In vivo; Substrate (aquarium); Chemistry; Particle (ecology); Drug delivery; Cell culture; Cell; In vitro; Materials science; Biochemistry; Biology; Biotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001375259,0.0001452209,0.0001470125,0.0001198633,0.00004764618,0.00002018376,0.0001419581,0.0002971103,0.00003231515],"category_scores_gemma":[0.0001209629,0.0001385645,0.00001662465,0.0001803387,0.0001649624,0.00004591611,0.0001545582,0.000292305,0.0000190269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002387332,"about_ca_system_score_gemma":0.000003314297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000598453,"about_ca_topic_score_gemma":0.00000358003,"domain_scores_codex":[0.9991636,0.00000723855,0.0001589574,0.0001929219,0.0001010584,0.0003762273],"domain_scores_gemma":[0.999639,0.00006348282,0.00001655451,0.000163928,0.00001076454,0.0001062139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000006516957,0.00001540732,0.002556155,0.000101249,0.00003827291,0.00003778273,0.00006950381,0.00002421678,0.9891474,0.001202432,0.00001399431,0.006787076],"study_design_scores_gemma":[0.000331663,0.00008659688,0.006272696,0.00005133825,0.00001513704,0.00008758144,0.00009759562,0.007292341,0.9843017,0.0001324792,0.001097447,0.0002334222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953217,0.001262977,0.00215405,0.0001756181,0.0001947193,0.00009505725,0.000008719078,0.0006819913,0.0001051495],"genre_scores_gemma":[0.9936057,0.000559025,0.005708037,0.000005393029,0.00003550965,0.000009557503,4.278626e-7,0.00002591297,0.00005045021],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007268124,"threshold_uncertainty_score":0.5650497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01685516580545583,"score_gpt":0.2289583478776135,"score_spread":0.2121031820721576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}