{"id":"W2122015259","doi":"10.1002/bit.23253","title":"Endothelial nanoparticle binding kinetics are matrix and size dependent","year":2011,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"3D Printing in Biomedical Research","field":"Engineering","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; Foothills Medical Centre; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Internalization; Nanoparticle; Endocytosis; Biophysics; Umbilical vein; Nanotechnology; Particle size; In vivo; Substrate (aquarium); Chemistry; Particle (ecology); Drug delivery; Cell culture; Cell; In vitro; Materials science; Biochemistry; Biology; Biotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007661785,0.00033766,0.0004393667,0.0003181845,0.0003146752,0.0007511388,0.0003592288,0.0005654565,0.001727985],"category_scores_gemma":[0.002599407,0.0004481605,0.0003193783,0.0002433363,0.0003105951,0.0006788119,0.0002373117,0.0007918084,0.001050392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006963305,"about_ca_system_score_gemma":0.0004986918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00365857,"about_ca_topic_score_gemma":0.004184506,"domain_scores_codex":[0.9991542,0.0001372429,0.00004686604,0.0001948856,0.0003579448,0.0001089491],"domain_scores_gemma":[0.9974732,0.001462914,0.0003116861,0.0001597689,0.0005214605,0.0000710386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001199305,0.00005760246,0.001837722,0.0000863262,0.00002685685,0.00007757612,0.000101396,0.001136248,0.9864971,0.0004502138,0.0002308049,0.009378189],"study_design_scores_gemma":[0.00000967962,0.0001728324,0.01476806,0.00001101152,0.00002875209,0.0003130249,0.00005680133,0.0183658,0.9622251,0.0003440091,0.003663362,0.00004157656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9093489,0.005575504,0.07600696,0.000404013,0.00006374352,0.00009745696,0.0005235661,0.0004224682,0.007557438],"genre_scores_gemma":[0.9796535,0.002030939,0.01072215,0.0001591621,0.00001226141,0.00008677476,0.0004117242,0.0001033961,0.006820044],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00365857,"threshold_uncertainty_score":0.007274508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01685516580545583,"score_gpt":0.2289583478776135,"score_spread":0.2121031820721576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}