{"id":"W2122044425","doi":"10.1002/jat.3225","title":"Functional expressions of adenosine triphosphate‐binding cassette transporters during the development of zebrafish embryos and their effects on the detoxification of cadmium chloride and β‐naphthoflavone","year":2015,"lang":"en","type":"article","venue":"Journal of Applied Toxicology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Natural Science Foundation of China","keywords":"Zebrafish; ATP-binding cassette transporter; Multidrug resistance-associated protein 2; Efflux; Biology; Embryo; Cell biology; Transporter; Toxicity; Adenosine triphosphate; Biochemistry; Chemistry; Pharmacology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001139198,0.0003026466,0.0002004631,0.0003480092,0.0001883928,0.0002130228,0.00012247,0.0002956083,0.001114684],"category_scores_gemma":[0.0001221681,0.0002477359,0.0003569346,0.0001398499,0.0002681684,0.0003546809,0.0001973237,0.0005266098,0.0002373183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004957091,"about_ca_system_score_gemma":0.0003063386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003899058,"about_ca_topic_score_gemma":0.005590086,"domain_scores_codex":[0.9998944,0.000009027284,0.00001137869,0.00003110523,0.00002689729,0.00002726617],"domain_scores_gemma":[0.9999087,0.00001091811,0.00002978613,0.000004673103,0.00002119514,0.00002468347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000752322,0.000005309964,0.0005649035,0.00002671889,0.000003011964,0.00009145334,0.00005381436,0.00002796062,0.998445,0.00007045064,0.00002869171,0.0006076333],"study_design_scores_gemma":[0.00002677736,0.0004757898,0.09003003,0.00002531769,0.00005780596,0.0002974885,0.0002378632,0.0009474169,0.9045647,0.0001357925,0.003167919,0.000033234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992765,0.001890023,0.001731322,0.0001412583,0.00002865025,0.000028336,0.0009101842,0.00005031754,0.002455016],"genre_scores_gemma":[0.9891869,0.001305285,0.001743734,0.0000853266,0.000008089827,0.00009643786,0.0006640671,0.00002008109,0.006889928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003899058,"threshold_uncertainty_score":0.007752717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02198003834357894,"score_gpt":0.2306706120255747,"score_spread":0.2086905736819958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}