{"id":"W2122059243","doi":"10.1177/2040620715571077","title":"Targeting polo-like kinase 1 in acute myeloid leukemia","year":2015,"lang":"en","type":"review","venue":"Therapeutic Advances in Hematology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"PLK1; Medicine; Cytarabine; Myeloid leukemia; Leukemia; Polo-like kinase; Myeloid; Clinical trial; Oncology; Cancer research; Internal medicine; Cell cycle; Pharmacology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003952169,0.0005471819,0.001063208,0.001955281,0.0001958048,0.0006556369,0.0006965483,0.0005935172,0.003694657],"category_scores_gemma":[0.0003919551,0.0002264238,0.0004932802,0.001559862,0.0002555743,0.0009186275,0.0005939541,0.001352585,0.002088411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003696219,"about_ca_system_score_gemma":0.0005950182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006487506,"about_ca_topic_score_gemma":0.001593948,"domain_scores_codex":[0.9998792,0.00001894203,0.00001941569,0.00001907422,0.00005081886,0.00001255294],"domain_scores_gemma":[0.9998804,0.00004412118,0.00002703898,0.000003300827,0.00003153839,0.00001347918],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009190451,0.00007257298,0.0001365354,0.02106361,0.0001158434,0.0001797894,0.00005108227,0.0002762121,0.002235463,0.001982018,0.02369127,0.9501036],"study_design_scores_gemma":[0.00003761232,0.0001193926,0.0006597836,0.003441125,0.0001581684,0.00121089,0.00003930615,0.00007566602,0.0005306396,0.001164476,0.9925494,0.0000135729],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001634005,0.9987406,0.00006281251,0.000133741,0.0000991628,0.000005940747,0.00001610937,0.000005530593,0.0007727172],"genre_scores_gemma":[0.0006768238,0.9984877,0.0001043048,0.0001435938,0.0000577613,0.000005379626,0.00003362462,0.000001039595,0.0004897164],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003694657,"threshold_uncertainty_score":0.01235986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05368819906423131,"score_gpt":0.4039952893888705,"score_spread":0.3503070903246392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}