{"id":"W2122111008","doi":"10.1111/j.1600-0854.2011.01160.x","title":"Hydrophobic‐Domain‐Dependent Protein–Protein Interactions Mediate the Localization of GPAT Enzymes to ER Subdomains","year":2011,"lang":"en","type":"article","venue":"Traffic","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; McMaster University; University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; U.S. Department of Agriculture","keywords":"Endoplasmic reticulum; Biology; Protein–protein interaction; Organelle; Cell biology; Acyltransferase; Signal transducing adaptor protein; Colocalization; Biochemistry; Protein domain; Unfolded protein response; Enzyme; Ubiquitin; Biophysics; Signal transduction; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006941347,0.0001749694,0.0001515521,0.00008198911,0.0001342531,0.0002281381,0.0001198939,0.0001688825,0.0008198079],"category_scores_gemma":[0.00008205145,0.0001144391,0.0002355166,0.00009920172,0.0001357823,0.0002986726,0.0003462952,0.0002655402,0.0006263118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001716758,"about_ca_system_score_gemma":0.00008624646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003214991,"about_ca_topic_score_gemma":0.0005259183,"domain_scores_codex":[0.9999347,0.000007966712,0.000004427783,0.00002122419,0.00001399768,0.00001780893],"domain_scores_gemma":[0.999928,0.00001133772,0.0000237273,0.00001168458,0.000008424344,0.00001677206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003896569,0.000006399355,0.0006422222,0.00001453228,0.000002848928,0.00006880586,0.000014783,0.00002286746,0.9985279,0.00006760385,0.00001169445,0.0005814011],"study_design_scores_gemma":[0.00001664776,0.0001102737,0.06969298,0.000004476797,0.00001473956,0.0007822266,0.00009072407,0.002311785,0.9242951,0.0001522345,0.002521599,0.00000727467],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997041,0.0003425431,0.001837058,0.0000266627,0.000003011727,0.000005753611,0.00006126028,0.00002588154,0.0006568344],"genre_scores_gemma":[0.9976745,0.0001755501,0.001005143,0.00001677964,0.000003091436,0.000007346185,0.0002100769,0.000007545891,0.000899988],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008198079,"threshold_uncertainty_score":0.002742529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01401457898036405,"score_gpt":0.2217756390481325,"score_spread":0.2077610600677685,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}