{"id":"W2122162695","doi":"10.2353/ajpath.2009.080539","title":"Mouse Pancreatic Islets Are Resistant to Indoleamine 2,3 Dioxygenase-Induced General Control Nonderepressible-2 Kinase Stress Pathway and Maintain Normal Viability and Function","year":2008,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; University of British Columbia","funders":"Canadian Institutes of Health Research; Edmonton Civic Employees Charitable Assistance Fund; University of Alberta","keywords":"Islet; Indoleamine 2,3-dioxygenase; Immune system; Transplantation; Insulin; Kinase; Endocrinology; Cell biology; Biology; Cancer research; Internal medicine; Medicine; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002312801,0.0006177347,0.0002466485,0.0006129903,0.0001859566,0.0006017623,0.0003235493,0.0004123327,0.002189949],"category_scores_gemma":[0.0001650631,0.0003160257,0.0003622161,0.0002354234,0.0002809504,0.0004396968,0.0002466212,0.001043733,0.0008672167],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002927163,"about_ca_system_score_gemma":0.0001792714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003693552,"about_ca_topic_score_gemma":0.0007649602,"domain_scores_codex":[0.9997626,0.00002299341,0.00002518692,0.00005414928,0.00006657281,0.00006844001],"domain_scores_gemma":[0.9995684,0.00003362758,0.0001573075,0.0000810541,0.00003083122,0.0001287091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001913861,0.0000266136,0.0002361001,0.00001200206,0.000005285178,0.00004878148,0.00001333454,0.0000242017,0.9986524,0.000173684,0.00003914983,0.0005771257],"study_design_scores_gemma":[0.0000388887,0.0002187366,0.007654884,0.00000740476,0.00002294401,0.0003719428,0.00004906728,0.0003505723,0.9883472,0.0001493795,0.002782229,0.00000669821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989926,0.001493331,0.004413629,0.0001980215,0.00007366473,0.00004370909,0.001365708,0.0003249338,0.002161095],"genre_scores_gemma":[0.9832411,0.0008140994,0.003406921,0.0001131645,0.00002110347,0.00007129005,0.001937283,0.000139297,0.01025565],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002189949,"threshold_uncertainty_score":0.007326186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01180287074298989,"score_gpt":0.2364998785535716,"score_spread":0.2246970078105817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}