{"id":"W2122203297","doi":"10.1093/hmg/ddq156","title":"Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes","year":2010,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":198,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Center for Research Resources; National Institute of Dental and Craniofacial Research; National Institute of Environmental Health Sciences; National Human Genome Research Institute; National Institute on Drug Abuse; National Heart, Lung, and Blood Institute; National Cancer Institute; National Institute on Alcohol Abuse and Alcoholism; American Heart Association; Canadian Institutes of Health Research; U.S. Public Health Service; National Institutes of Health; Fondation Leducq; Broad Institute; National Institute of Diabetes and Digestive and Kidney Diseases; Johns Hopkins University; Amgen; School of Medicine, Boston University; Massachusetts General Hospital; Donald W. Reynolds Foundation","keywords":"Biology; Genome-wide association study; Type 2 diabetes; Locus (genetics); Genetics; Insulin resistance; Allele; SNP; Genetic association; Single-nucleotide polymorphism; Case-control study; Gene; Diabetes mellitus; Internal medicine; Endocrinology; Genotype; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007187058,0.0007895597,0.0004921572,0.001553097,0.0004006573,0.0008465346,0.0005400772,0.0006811575,0.002909145],"category_scores_gemma":[0.003290137,0.0003851832,0.0005704889,0.001621925,0.000397634,0.0001813572,0.0003447649,0.0004739803,0.0003615507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001655741,"about_ca_system_score_gemma":0.0001382447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002231993,"about_ca_topic_score_gemma":0.001615974,"domain_scores_codex":[0.9993535,0.000212682,0.00005901827,0.0002086366,0.0001018815,0.00006440291],"domain_scores_gemma":[0.9986602,0.0003728179,0.0006488357,0.0001037256,0.00007483336,0.0001395551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001452937,0.0001140048,0.9746738,0.00005264854,0.0008190908,0.001738774,0.0002523063,0.0005846901,0.01193375,0.0001838053,0.0004947457,0.007699579],"study_design_scores_gemma":[0.0001537615,0.0001998966,0.9933593,0.00002368348,0.0003182301,0.002949991,0.00008677744,0.000768122,0.0008600825,0.0005097348,0.0007528875,0.00001750174],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981626,0.000665426,0.0004360295,0.0001075845,0.00001347369,0.000008941766,0.0002368745,0.00002743348,0.0003417068],"genre_scores_gemma":[0.9984865,0.0002984878,0.0005575813,0.0000421964,0.0000441485,0.00001232819,0.0003014055,0.000009167341,0.0002480245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002909145,"threshold_uncertainty_score":0.009732068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01160239225487413,"score_gpt":0.2526516502146008,"score_spread":0.2410492579597267,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}