{"id":"W2122203718","doi":"10.1016/s0168-8278(08)60820-x","title":"818 VIRAL KINETICS AND PHARMACODYNAMICS OF ALBINTERFERON ALFA-2B IN INTERFERON TREATMENT-NAIVE PATIENTS WITH GENOTYPE 1, CHRONIC HEPATITIS C","year":2008,"lang":"en","type":"article","venue":"Journal of Hepatology","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Duke Clinical Research Institute; Bar-Ilan University; University of Alberta","keywords":"Medicine; Pharmacodynamics; NS5A; Chronic hepatitis; Genotype; Odds ratio; Interferon; Alpha interferon; Internal medicine; Hepatitis C; Interferon alfa; Gastroenterology; Immunology; Virology; Hepacivirus; Human immunodeficiency virus (HIV); Pharmacokinetics; Biology; Viral disease; Gene; Virus; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005402023,0.000332046,0.0008210208,0.0002364068,0.0002954184,0.0004995738,0.0001322947,0.0005015054,0.001126296],"category_scores_gemma":[0.002655324,0.0002772157,0.0003897792,0.0001941119,0.0002393201,0.0006276428,0.0001059092,0.0007134162,0.0003219149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004028839,"about_ca_system_score_gemma":0.0002376079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001015643,"about_ca_topic_score_gemma":0.001285054,"domain_scores_codex":[0.9997608,0.0001028422,0.00002457517,0.0000358564,0.0000334453,0.00004247961],"domain_scores_gemma":[0.9991453,0.0004171148,0.0001508355,0.00004508425,0.00004603952,0.0001956026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1304097,0.002710843,0.756109,0.0001862844,0.0006530591,0.001987351,0.0005716503,0.003223641,0.05194316,0.0002280872,0.001126834,0.05085037],"study_design_scores_gemma":[0.003535984,0.02786773,0.9535207,0.00002580792,0.000441205,0.002244484,0.0002537847,0.006056245,0.004562521,0.0002321289,0.001207301,0.00005206607],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992484,0.0002447524,0.00004834939,0.00004402308,0.000008649517,0.000009130727,0.00006371502,0.00000663894,0.0003261171],"genre_scores_gemma":[0.9993101,0.00009491099,0.000084304,0.00008945071,0.00001892573,0.00001065086,0.0001403816,0.0000047546,0.0002464287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001126296,"threshold_uncertainty_score":0.003767788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01019435162561861,"score_gpt":0.2480147691582139,"score_spread":0.2378204175325953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}