{"id":"W2122277086","doi":"10.1002/anie.201309684","title":"Turning Tryptophanase into Odor‐Generating Biosensors","year":2014,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Biosensors and Analytical Detection","field":"Engineering","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Biotinylation; Tryptophanase; Odor; Biochemistry; Chemistry; Biosensor; Enzyme; Analyte; Chromatography; Tryptophan; Amino acid; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002722452,0.0003529958,0.0002440238,0.0001710007,0.00009850567,0.0005196389,0.0005428354,0.0006528837,0.0008548831],"category_scores_gemma":[0.0004647574,0.0002530965,0.000260817,0.0001628935,0.0003150195,0.0005288449,0.000439643,0.0008908436,0.00064453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003649846,"about_ca_system_score_gemma":0.0001120733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002827734,"about_ca_topic_score_gemma":0.0003229774,"domain_scores_codex":[0.99977,0.00004312292,0.00001091386,0.0000508373,0.00008277174,0.0000424315],"domain_scores_gemma":[0.9998883,0.00003552544,0.00001720065,0.000008293344,0.00002943422,0.00002121446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002596127,0.00001675856,0.00005107742,0.00006313713,0.000005491591,0.00005153122,0.00002117202,0.0001249187,0.9918725,0.001210626,0.000246927,0.006309915],"study_design_scores_gemma":[0.000009083986,0.00007211167,0.0001390375,0.000007724793,0.000005726516,0.00007698894,0.00001342584,0.001529285,0.9896889,0.0003439959,0.008104174,0.000009525193],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6607347,0.01720211,0.2927807,0.002324689,0.001896072,0.0002651032,0.0005297961,0.002863534,0.0214034],"genre_scores_gemma":[0.8873997,0.007673683,0.093398,0.0008683483,0.0001514697,0.0001727166,0.0003309908,0.0001159885,0.009889122],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008548831,"threshold_uncertainty_score":0.002859831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007433748681862659,"score_gpt":0.2182892984053871,"score_spread":0.2108555497235245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}