{"id":"W2122277086","doi":"10.1002/anie.201309684","title":"Turning Tryptophanase into Odor‐Generating Biosensors","year":2014,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Biosensors and Analytical Detection","field":"Engineering","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Biotinylation; Tryptophanase; Odor; Biochemistry; Chemistry; Biosensor; Enzyme; Analyte; Chromatography; Tryptophan; Amino acid; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001481033,0.0001293104,0.0001064884,0.00008818859,0.00007385782,0.00007223571,0.0001758645,0.00009848367,0.0001801373],"category_scores_gemma":[0.0001692392,0.0001296092,0.00005318443,0.000105,0.00002865258,0.0002594517,0.00003753551,0.0001625622,0.0000717363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000825918,"about_ca_system_score_gemma":0.000004552699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001944213,"about_ca_topic_score_gemma":0.00001405637,"domain_scores_codex":[0.9991972,0.00001193323,0.0002071048,0.000212403,0.0002245471,0.0001468074],"domain_scores_gemma":[0.9995796,0.00005975792,0.00003821461,0.0001747396,0.00007587532,0.00007180506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00000850899,0.00002352749,0.0000571917,0.00003679805,0.00006928533,0.000004392638,0.00009935262,0.005307271,0.964229,0.0004169007,0.01182529,0.01792244],"study_design_scores_gemma":[0.0001887505,0.00001268676,0.000126948,0.00003168478,0.00001096704,0.000007010616,0.00002630952,0.2501016,0.7318985,0.0006596256,0.0167971,0.0001387557],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6810491,0.0002222517,0.2669917,0.001772202,0.008258837,0.0001697208,0.00007990716,0.001213907,0.04024232],"genre_scores_gemma":[0.9938622,0.00004328959,0.001837958,0.0001809928,0.003578844,0.000006076195,0.0002969863,0.00002420395,0.0001694074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3128131,"threshold_uncertainty_score":0.5285309,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007433748681862659,"score_gpt":0.2182892984053871,"score_spread":0.2108555497235245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}