{"id":"W2122343496","doi":"10.1093/annonc/mdl042","title":"A phase I study of the humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody EMD 72000 (matuzumab) in combination with paclitaxel in patients with EGFR-positive advanced non-small-cell lung cancer (NSCLC)","year":2006,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Paclitaxel; Pharmacokinetics; Neutropenia; Tolerability; Lung cancer; Epidermal growth factor receptor; Pharmacology; Rash; Internal medicine; Toxicity; Adverse effect; Gastroenterology; Chemotherapy; Oncology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00113139,0.001748376,0.002390902,0.000688888,0.0004512425,0.001201457,0.00123095,0.001439122,0.003063291],"category_scores_gemma":[0.0009486646,0.0008570513,0.001402052,0.0006096613,0.001089653,0.001103607,0.0003367675,0.003850733,0.001048365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001007655,"about_ca_system_score_gemma":0.001419926,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001909132,"about_ca_topic_score_gemma":0.004062487,"domain_scores_codex":[0.9996834,0.0001389829,0.00001203455,0.00005853956,0.00002742375,0.00007967114],"domain_scores_gemma":[0.9993905,0.0001212828,0.00008163197,0.00004927385,0.00003073462,0.0003265718],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7422348,0.0975868,0.004488947,0.0008071042,0.001506046,0.0003872405,0.0004617786,0.00496433,0.04007448,0.0005627877,0.005140976,0.1017848],"study_design_scores_gemma":[0.5364213,0.4468856,0.00703183,0.00002646457,0.0005561026,0.0003209728,0.00007842667,0.001829986,0.004320249,0.0002142683,0.00227522,0.0000396569],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920092,0.001925694,0.0007022627,0.0005572953,0.0002531486,0.001533064,0.0007725258,0.0001904113,0.002056317],"genre_scores_gemma":[0.9885894,0.002488949,0.001498524,0.0006644842,0.0002535318,0.001478305,0.001478349,0.00005396232,0.00349458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003063291,"threshold_uncertainty_score":0.01024771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01670430655179582,"score_gpt":0.3690962874268092,"score_spread":0.3523919808750133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}