{"id":"W2122343496","doi":"10.1093/annonc/mdl042","title":"A phase I study of the humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody EMD 72000 (matuzumab) in combination with paclitaxel in patients with EGFR-positive advanced non-small-cell lung cancer (NSCLC)","year":2006,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Paclitaxel; Pharmacokinetics; Neutropenia; Tolerability; Lung cancer; Epidermal growth factor receptor; Pharmacology; Rash; Internal medicine; Toxicity; Adverse effect; Gastroenterology; Chemotherapy; Oncology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001093585,0.0002248623,0.0006621868,0.0002248253,0.00006515397,0.0000058449,0.0001115209,0.0000955014,0.00003813549],"category_scores_gemma":[0.00001902561,0.0001465954,0.00005737902,0.0004544867,0.0001110627,0.0001535143,0.0000316497,0.0001966868,7.245353e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003063859,"about_ca_system_score_gemma":0.0005757444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003975159,"about_ca_topic_score_gemma":0.00181165,"domain_scores_codex":[0.9983941,0.0001586357,0.0005350685,0.0003234225,0.0002886375,0.0003001226],"domain_scores_gemma":[0.9986037,0.0001111706,0.0004826272,0.0002079571,0.0005404045,0.00005412601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003987411,0.02546414,0.9605815,0.0001046041,0.0002746796,0.00003447618,0.004573987,0.0001611747,0.002567293,0.00003755612,0.0001361496,0.00207704],"study_design_scores_gemma":[0.06237244,0.01466284,0.915531,0.000330443,0.000201993,0.00000173236,0.0008557172,0.00007892969,0.005770687,0.00001224641,0.00003323752,0.0001486718],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954994,0.0001575897,0.00002368092,0.0005842812,0.00008430204,0.002616545,0.0001503633,0.00001046476,0.0008733362],"genre_scores_gemma":[0.9990742,0.00004037699,0.000237158,0.0001813566,0.0000220057,0.0001641312,0.0001591821,0.00002828125,0.00009334673],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05838503,"threshold_uncertainty_score":0.6009278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01670430655179582,"score_gpt":0.3690962874268092,"score_spread":0.3523919808750133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}