{"id":"W2122377860","doi":"10.1038/srep12922","title":"The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Queen's University Belfast; Queen's University; Cancer Research UK","keywords":"Imiquimod; TLR7; Immune system; Innate immune system; Immunology; Biology; Mediator; Cancer research; Cell biology; Toll-like receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002377855,0.0002872137,0.0002738397,0.0002122505,0.0001743253,0.0002272385,0.0001385202,0.0002253893,0.001433672],"category_scores_gemma":[0.00007555646,0.0001297663,0.0003451277,0.0001551693,0.0001652762,0.0001516573,0.0001231561,0.0003803386,0.0005174601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002083707,"about_ca_system_score_gemma":0.0002016434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007275132,"about_ca_topic_score_gemma":0.0008778839,"domain_scores_codex":[0.9998185,0.00004627495,0.00002433375,0.00002041185,0.00004512013,0.00004535911],"domain_scores_gemma":[0.9999303,0.00002255877,0.000008245207,0.00001226539,0.00001329907,0.00001338482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001121219,0.00005721705,0.00006970926,0.00003846749,0.000002872781,0.00002871473,0.00001393547,0.00002238236,0.9991336,0.00002219347,0.00001784151,0.0004809611],"study_design_scores_gemma":[0.00002033139,0.000764777,0.002741514,0.000004665801,0.000009387563,0.0001360529,0.00003447902,0.0002518826,0.9953611,0.0000164439,0.0006576632,0.000001720566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936977,0.002060149,0.001323466,0.00007683782,0.0000647048,0.00007110581,0.0003093324,0.00003336218,0.002363326],"genre_scores_gemma":[0.9944635,0.001272402,0.001378694,0.00005315724,0.00001684391,0.00005357222,0.0004292711,0.000007194805,0.002325352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001433672,"threshold_uncertainty_score":0.004796088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06962550403960317,"score_gpt":0.3465192164833002,"score_spread":0.276893712443697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}