{"id":"W2122378943","doi":"10.1002/emmm.200900055","title":"A non‐enzymatic function of 17β‐hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival","year":2010,"lang":"en","type":"article","venue":"EMBO Molecular Medicine","topic":"Aldose Reductase and Taurine","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Stiftelsen för Strategisk Forskning; Ontario Genomics Institute; Canadian Institutes of Health Research; National Institute for Health and Care Research; Ontario Genomics; Genome Canada; Ontario Innovation Trust; Wellcome Trust; GlaxoSmithKline","keywords":"Enzyme; Dehydrogenase; Biology; Function (biology); Mitochondrion; Hydroxysteroid dehydrogenase; Cell biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002243521,0.0002059701,0.0003168051,0.00006424657,0.00004959414,0.000006826775,0.0001296671,0.0002188552,0.0001049955],"category_scores_gemma":[0.0001976269,0.0001724879,0.0000869934,0.0001110793,0.0001760248,0.000005208508,0.00006746406,0.0001767964,0.000006267893],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005220728,"about_ca_system_score_gemma":0.00008742682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003938633,"about_ca_topic_score_gemma":0.00002582933,"domain_scores_codex":[0.9988606,0.00003577566,0.000323133,0.0003733014,0.0001867548,0.0002204637],"domain_scores_gemma":[0.9990562,0.00001971198,0.0001461365,0.0004456965,0.0001933084,0.0001389154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004110235,0.00007053478,0.00005601338,0.0001376971,0.00008593922,0.000006153053,0.0000738271,9.956183e-7,0.9959859,0.00006188703,0.002686588,0.000423413],"study_design_scores_gemma":[0.002628773,0.001521791,0.000110349,0.00003998634,0.0001706319,0.00002130217,0.00007362811,0.000182772,0.9771035,0.0002932674,0.01766974,0.0001843087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927029,0.0009158839,0.003991887,0.0003457209,0.0008138741,0.0004288381,0.00002138981,0.000009533198,0.0007700006],"genre_scores_gemma":[0.9970548,0.00004442659,0.001043417,0.0002886054,0.0006261325,0.00002502414,0.000278559,0.0000337925,0.000605225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01888247,"threshold_uncertainty_score":0.7033852,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01116407996386931,"score_gpt":0.2602189786738495,"score_spread":0.2490548987099802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}