{"id":"W2122378943","doi":"10.1002/emmm.200900055","title":"A non‐enzymatic function of 17β‐hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival","year":2010,"lang":"en","type":"article","venue":"EMBO Molecular Medicine","topic":"Aldose Reductase and Taurine","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Stiftelsen för Strategisk Forskning; Ontario Genomics Institute; Canadian Institutes of Health Research; National Institute for Health and Care Research; Ontario Genomics; Genome Canada; Ontario Innovation Trust; Wellcome Trust; GlaxoSmithKline","keywords":"Enzyme; Dehydrogenase; Biology; Function (biology); Mitochondrion; Hydroxysteroid dehydrogenase; Cell biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001232689,0.0003901774,0.0002427193,0.0001801388,0.0001634949,0.0003576668,0.0001839238,0.0001872976,0.0009045511],"category_scores_gemma":[0.0001798112,0.0001313941,0.0001940715,0.0001089175,0.0003560929,0.0001738177,0.0001834364,0.0002267777,0.0006641602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003782769,"about_ca_system_score_gemma":0.0002987341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005529312,"about_ca_topic_score_gemma":0.0008696317,"domain_scores_codex":[0.9998966,0.00001666831,0.00001072185,0.00002201581,0.00003187901,0.00002216114],"domain_scores_gemma":[0.9998146,0.00001966554,0.00006371435,0.00002822054,0.00002564168,0.00004822358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001347731,0.000008467284,0.0008782749,0.00004331404,0.000009067088,0.0002330761,0.00001256482,0.00003481915,0.9957496,0.0001785262,0.00005055972,0.002667039],"study_design_scores_gemma":[0.00002046309,0.0002277722,0.01729664,0.00001131305,0.00002266388,0.002813498,0.00006056944,0.0002132778,0.9721024,0.0001965542,0.007028617,0.000006101582],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984911,0.007420804,0.004566182,0.0002094423,0.00008155392,0.000012848,0.0003909206,0.0001630342,0.002244189],"genre_scores_gemma":[0.9933789,0.002371538,0.001344307,0.00002123858,0.00001252213,0.000008586566,0.0004370649,0.00001501818,0.002410739],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009045511,"threshold_uncertainty_score":0.003026068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01116407996386931,"score_gpt":0.2602189786738495,"score_spread":0.2490548987099802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}