{"id":"W2122398847","doi":"10.3324/haematol.2013.096859","title":"The importance of calcium in the regulation of megakaryocyte function","year":2014,"lang":"en","type":"article","venue":"Haematologica","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Hospital Foundation","funders":"National Institute of Biomedical Imaging and Bioengineering","keywords":"Megakaryocyte; Cell biology; Extracellular; ORAI1; Calcium; Calcium in biology; Thrombopoiesis; Calcium signaling; Chemistry; Phospholipase C; Intracellular; Biochemistry; Biology; Voltage-dependent calcium channel; Signal transduction; Stem cell; Progenitor cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001637375,0.0002452701,0.0002673194,0.0002858276,0.0002892855,0.0006274634,0.0002490793,0.0004997732,0.0006345801],"category_scores_gemma":[0.0002262783,0.0001145095,0.0001278334,0.000222581,0.0002936006,0.0003045552,0.0003324277,0.0004029895,0.0001475137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002975718,"about_ca_system_score_gemma":0.0002919223,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004268485,"about_ca_topic_score_gemma":0.0005693677,"domain_scores_codex":[0.9998556,0.00002738379,0.00001391708,0.00003206494,0.00003673172,0.00003428668],"domain_scores_gemma":[0.9999115,0.00002954895,0.00002260113,0.000007257494,0.00001225427,0.00001670277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007816092,0.0000492793,0.001541357,0.000404215,0.00002011955,0.0009498414,0.0001128261,0.0002701297,0.9711482,0.002349256,0.0003009333,0.02207232],"study_design_scores_gemma":[0.000330242,0.001662513,0.08711702,0.0002180864,0.0002023614,0.006127871,0.0003778897,0.003094509,0.8398452,0.005050133,0.05591743,0.00005677887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7773767,0.2042998,0.007468247,0.001650759,0.0002178751,0.00008661194,0.0003833862,0.0001265024,0.008390124],"genre_scores_gemma":[0.9666522,0.02929014,0.002300821,0.0001361309,0.0001400348,0.00004038761,0.0001304885,0.00001314266,0.001296581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006345801,"threshold_uncertainty_score":0.002159059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0248970509552376,"score_gpt":0.273511144694303,"score_spread":0.2486140937390655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}