{"id":"W2122431358","doi":"10.1128/jvi.79.20.13105-13115.2005","title":"Inhibitors of Respiratory Syncytial Virus Replication Target Cotranscriptional mRNA Guanylylation by Viral RNA-Dependent RNA Polymerase","year":2005,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":131,"is_retracted":false,"has_abstract":true,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"","keywords":"Biology; Polymerase; Virology; RNA-dependent RNA polymerase; RNA polymerase; Subgenomic mRNA; RNA; Virus; Viral replication; Molecular biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004924932,0.0001496626,0.0002739755,0.0001411737,0.00005807584,0.000008081231,0.0001682463,0.000261616,0.0000141572],"category_scores_gemma":[0.00009356195,0.0001325913,0.0002019669,0.00007665304,0.0001474441,0.00001984827,0.00003121094,0.0001983077,0.000001520137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000445398,"about_ca_system_score_gemma":0.00008374443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009584141,"about_ca_topic_score_gemma":0.00001167799,"domain_scores_codex":[0.9984602,0.0001411143,0.0007315443,0.0002482944,0.0002467156,0.0001721276],"domain_scores_gemma":[0.9986454,0.00001412444,0.0007570556,0.0002802229,0.00022486,0.0000783213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000471031,0.000166386,0.0003396434,0.000004151009,0.00008407459,0.000003418258,0.00001347947,0.0001269234,0.9884531,0.00002857476,0.003372401,0.006936841],"study_design_scores_gemma":[0.0005940408,0.0008850735,0.0005161514,0.000009293914,0.00005708068,0.00004989442,0.00001010819,0.0000672056,0.9775248,0.0001220196,0.02004173,0.0001225582],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886741,0.001878377,0.008381698,0.0006760408,0.0001323295,0.00007218445,0.00004537761,0.000009504269,0.0001303828],"genre_scores_gemma":[0.9948508,0.000307886,0.003261753,0.0006774809,0.0007540283,0.000001846475,0.00004962161,0.00001547297,0.00008117724],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01666933,"threshold_uncertainty_score":0.5406915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008178265878795807,"score_gpt":0.2710473671977792,"score_spread":0.2628691013189833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}