{"id":"W2122431358","doi":"10.1128/jvi.79.20.13105-13115.2005","title":"Inhibitors of Respiratory Syncytial Virus Replication Target Cotranscriptional mRNA Guanylylation by Viral RNA-Dependent RNA Polymerase","year":2005,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":131,"is_retracted":false,"has_abstract":true,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"","keywords":"Biology; Polymerase; Virology; RNA-dependent RNA polymerase; RNA polymerase; Subgenomic mRNA; RNA; Virus; Viral replication; Molecular biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002199546,0.00082195,0.0005544263,0.0002675877,0.0001854583,0.0002901219,0.0003094451,0.0002643165,0.0008316371],"category_scores_gemma":[0.0001704555,0.0002425548,0.0004257011,0.0001445193,0.0002112689,0.0001569138,0.0002139959,0.0006495208,0.0003876472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003385552,"about_ca_system_score_gemma":0.0002516838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004204914,"about_ca_topic_score_gemma":0.001176496,"domain_scores_codex":[0.9997852,0.00003456813,0.00001705394,0.00004090607,0.00007790211,0.00004436088],"domain_scores_gemma":[0.9998794,0.00003961602,0.00003929023,0.00001128831,0.00001615046,0.00001428799],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007439138,0.0000596909,0.0001299116,0.00009418007,0.00001224886,0.0000348868,0.000009937882,0.0002705414,0.993138,0.0001404063,0.00005041889,0.005985416],"study_design_scores_gemma":[0.00003398581,0.0008892299,0.0009199308,0.000009655241,0.00002500866,0.0001944346,0.000006593005,0.001074196,0.9926603,0.00004236702,0.004137514,0.000006887109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.924314,0.0328862,0.03311132,0.0002433107,0.0001825785,0.0005652239,0.000763568,0.0004543067,0.007479564],"genre_scores_gemma":[0.9642731,0.01809617,0.01283041,0.0001006594,0.00004107593,0.0001753937,0.000970108,0.00005572598,0.003457461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008316371,"threshold_uncertainty_score":0.002782106,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008178265878795807,"score_gpt":0.2710473671977792,"score_spread":0.2628691013189833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}