{"id":"W2122438075","doi":"10.1186/gb-2012-13-11-r105","title":"A phenotypic screening platform to identify small molecule modulators of Chlamydomonas reinhardtiigrowth, motility and photosynthesis","year":2012,"lang":"en","type":"article","venue":"Genome biology","topic":"Algal biology and biofuel production","field":"Energy","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"National Human Genome Research Institute","keywords":"Chlamydomonas reinhardtii; Chlamydomonas; Motility; Photosynthesis; Phototaxis; Biology; Small molecule; Computational biology; Cilium; Phenotype; Cell biology; Phenotypic screening; Biophysics; Gene; Botany; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003826434,0.000602595,0.0004033129,0.0003902244,0.0003174364,0.0002592925,0.000269081,0.0002664916,0.001346195],"category_scores_gemma":[0.0006549562,0.0002006409,0.0004070357,0.0002390018,0.0001766154,0.0001678162,0.0002782081,0.000295577,0.0003108937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003230396,"about_ca_system_score_gemma":0.0005470145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002062419,"about_ca_topic_score_gemma":0.003709827,"domain_scores_codex":[0.999836,0.00003750128,0.000009100018,0.00004079524,0.00006176468,0.00001496163],"domain_scores_gemma":[0.9997526,0.0001135269,0.00004520169,0.00003117741,0.00003429158,0.00002327603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001811702,0.0002351682,0.003739947,0.00008750071,0.00007728202,0.0001576427,0.00001917428,0.0216013,0.9312565,0.0008237564,0.0004709534,0.04134962],"study_design_scores_gemma":[0.000104876,0.001558688,0.01329374,0.000008262697,0.0001146743,0.00028174,0.00002344928,0.1821854,0.7986078,0.000730867,0.003047329,0.00004298922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8543183,0.0005991223,0.1328264,0.0003634585,0.00003058364,0.0004004473,0.004115652,0.003337674,0.004008365],"genre_scores_gemma":[0.9252559,0.000322998,0.07082857,0.00008619711,0.000007798834,0.0002614334,0.001721741,0.00004730984,0.00146802],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002062419,"threshold_uncertainty_score":0.004503489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03446669430251664,"score_gpt":0.2651799345159726,"score_spread":0.230713240213456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}