{"id":"W2122547951","doi":"10.1161/circresaha.114.305777","title":"IRF2BP2 Reduces Macrophage Inflammation and Susceptibility to Atherosclerosis","year":2015,"lang":"en","type":"article","venue":"Circulation Research","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Inflammation; ABCA1; Cholesterol; Apolipoprotein B; Biology; Internal medicine; Endocrinology; Immunology; Fibrinogen; Lipoprotein; Macrophage; Cancer research; Medicine; Gene; Transporter; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000474509,0.0006199766,0.0004871954,0.0003707388,0.0001771974,0.0002707269,0.0003732997,0.0005927467,0.003016124],"category_scores_gemma":[0.0004691956,0.0001859197,0.0002636362,0.0002367005,0.0002947289,0.0001157903,0.0002290959,0.0004195959,0.0004307556],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001757548,"about_ca_system_score_gemma":0.0001886652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003428856,"about_ca_topic_score_gemma":0.0004127932,"domain_scores_codex":[0.9997764,0.00008782983,0.00001194497,0.0000449275,0.00004644091,0.00003239453],"domain_scores_gemma":[0.9997354,0.00005829997,0.00009681627,0.00002887778,0.00001958605,0.00006112786],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01528006,0.001747076,0.1179987,0.000558298,0.0006715234,0.001286699,0.00008354371,0.0006753747,0.8267151,0.0006194853,0.002338811,0.03202542],"study_design_scores_gemma":[0.002517873,0.01444575,0.7549082,0.0001515873,0.001407549,0.01354086,0.0001696345,0.00628286,0.1941301,0.001074594,0.01130986,0.00006116155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943683,0.002348459,0.001367364,0.0003153237,0.00003251606,0.00004147555,0.0003216889,0.0001121859,0.001092747],"genre_scores_gemma":[0.9966808,0.00060764,0.0009388086,0.0001128115,0.00003784354,0.00003784463,0.000337181,0.00002031615,0.001226771],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003016124,"threshold_uncertainty_score":0.01008993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2083040683868698,"score_gpt":0.4193073996544318,"score_spread":0.211003331267562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}