{"id":"W2122550330","doi":"10.1128/aac.01510-06","title":"Reduced Susceptibility to Polyenes Associated with a Missense Mutation in the <i>ERG6</i> Gene in a Clinical Isolate of <i>Candida glabrata</i> with Pseudohyphal Growth","year":2006,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":109,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministère des Transports","funders":"","keywords":"Ergosterol; Complementation; Biology; Missense mutation; Gene; Mutation; Biochemistry; Candida glabrata; Sterol; Yeast; Microbiology; Molecular biology; Phenotype; Candida albicans","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009064131,0.0006822671,0.0004334804,0.0003648272,0.0002210072,0.0003469387,0.000251476,0.0006843246,0.000926132],"category_scores_gemma":[0.0003637685,0.0001377854,0.0004353983,0.0002599031,0.0002902156,0.00009458881,0.0002933935,0.0004858118,0.0003789815],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001773566,"about_ca_system_score_gemma":0.0001496591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00136208,"about_ca_topic_score_gemma":0.000731402,"domain_scores_codex":[0.9998079,0.00002012544,0.00002723346,0.00005245944,0.00005409119,0.00003827298],"domain_scores_gemma":[0.9998145,0.00003915161,0.00005795737,0.00001540006,0.00002146481,0.00005164721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003183911,0.00006751427,0.003835352,0.00006334073,0.00002267027,0.007530878,0.0000703344,0.00008699083,0.9856321,0.00004000233,0.00008818891,0.002244242],"study_design_scores_gemma":[0.0001245148,0.002080847,0.2243392,0.00004415878,0.000211019,0.143361,0.000362083,0.002421588,0.6227376,0.000137682,0.004105248,0.00007501482],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998447,0.0002828273,0.0004669529,0.00007732982,0.00001314246,0.00002556507,0.0002928093,0.00005052085,0.0003439227],"genre_scores_gemma":[0.998329,0.0001572948,0.0006109917,0.00005210999,0.0000109425,0.000007649544,0.0005164785,0.00002462995,0.0002908428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00136208,"threshold_uncertainty_score":0.003098249,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01185731883246304,"score_gpt":0.2742373620440501,"score_spread":0.2623800432115871,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}