{"id":"W2122563452","doi":"10.1261/rna.1039708","title":"Monocistronic mRNAs containing defective hepatitis C virus-like picornavirus internal ribosome entry site elements in their 5′ untranslated regions are efficiently translated in cells by a cap-dependent mechanism","year":2008,"lang":"en","type":"article","venue":"RNA","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; McGill University","keywords":"Picornavirus; Biology; Internal ribosome entry site; Untranslated region; Five prime untranslated region; Virology; Three prime untranslated region; Translation (biology); Mechanism (biology); Messenger RNA; Cell biology; Molecular biology; Genetics; RNA; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002828219,0.000294488,0.0005309673,0.0004543876,0.0001713221,0.00002265208,0.000165261,0.0002474198,0.0001804405],"category_scores_gemma":[0.00001874951,0.0002763068,0.0001587449,0.0005680072,0.0001366458,0.0001432271,0.00004567358,0.00111823,0.00008374805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005183403,"about_ca_system_score_gemma":0.0001482756,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01164281,"about_ca_topic_score_gemma":0.00619008,"domain_scores_codex":[0.9976729,0.000244796,0.0005979251,0.0004800777,0.0002788808,0.0007254473],"domain_scores_gemma":[0.9992548,0.00007238176,0.0001417307,0.0002944516,0.00009454705,0.0001420561],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001748449,0.001604302,0.2394684,0.00004525339,0.0004280084,0.001418688,0.005531911,0.0001492289,0.7470586,0.00006742504,0.0002374891,0.002242308],"study_design_scores_gemma":[0.0407311,0.006750563,0.2679315,0.002319166,0.0002685077,0.001068822,0.002689912,0.01385764,0.6588301,0.0006195062,0.003275287,0.001657869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950095,0.002346857,0.0009407827,0.0001579407,0.0002033451,0.0007816706,0.0001443881,0.00007062786,0.000344865],"genre_scores_gemma":[0.9960414,0.002998793,0.00003333169,0.0001616268,0.00002320209,0.00008735817,0.00009055146,0.00004171588,0.0005220875],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08822844,"threshold_uncertainty_score":0.9999689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0198520236031689,"score_gpt":0.2659372854795718,"score_spread":0.2460852618764029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}