{"id":"W2122643576","doi":"10.1093/toxsci/kfl090","title":"In Utero Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin Induces Amphiregulin Gene Expression in the Developing Mouse Ureter","year":2006,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Amphiregulin; Aryl hydrocarbon receptor; Epiregulin; Aryl hydrocarbon receptor nuclear translocator; Endocrinology; Internal medicine; Epidermal growth factor; Biology; Gene expression; Epidermal growth factor receptor; Chemistry; Receptor; Transcription factor; Gene; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001165153,0.0001972095,0.0001884523,0.0004490769,0.0001107185,0.000229208,0.0001285623,0.0002275438,0.0008840847],"category_scores_gemma":[0.00009018617,0.0002608653,0.0002496168,0.0001458745,0.0002390542,0.000131663,0.0001707373,0.0004362496,0.000260085],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003122003,"about_ca_system_score_gemma":0.0002059886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009086996,"about_ca_topic_score_gemma":0.00201506,"domain_scores_codex":[0.9998467,0.00001626494,0.00001219405,0.00004389269,0.00003789572,0.00004304012],"domain_scores_gemma":[0.999838,0.0000245877,0.0000595666,0.00001726882,0.00001516756,0.00004533114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00005851291,0.000008695742,0.0004463015,0.000007454685,0.000001941239,0.00004733389,0.0000114072,0.00001723929,0.9989482,0.00002381716,0.000008221146,0.000420953],"study_design_scores_gemma":[0.00001353287,0.000421537,0.02530667,0.000007542498,0.00001905145,0.0002893894,0.00004731795,0.0002820466,0.9725435,0.00003581474,0.001029392,0.000004157196],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966694,0.0008904038,0.001262102,0.00003031633,0.00001107033,0.00001622149,0.0002893092,0.00004792265,0.0007833812],"genre_scores_gemma":[0.9892173,0.001382421,0.002241448,0.00006513904,0.000009623386,0.00004966758,0.0007875734,0.00003315226,0.006213637],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009086996,"threshold_uncertainty_score":0.002957582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03076874175506311,"score_gpt":0.2734131109752075,"score_spread":0.2426443692201444,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}