{"id":"W2122680973","doi":"10.1111/jne.12225","title":"Direct Regulation of Gonadotrophin‐Releasing Hormone (GnRH) Transcription By RF‐Amide‐Related Peptide‐3 and Kisspeptin in A Novel GnRH‐Secreting Cell Line, mHypoA‐GnRH/GFP","year":2014,"lang":"en","type":"article","venue":"Journal of Neuroendocrinology","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Kisspeptin; Internal medicine; Endocrinology; Gonadotropin-releasing hormone; Messenger RNA; Hypothalamus; Receptor; Biology; Hormone; Chemistry; Luteinizing hormone; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001278111,0.0002145465,0.000294191,0.0001169044,0.0001363808,0.000219651,0.0001846252,0.0002461338,0.0006309072],"category_scores_gemma":[0.00009979519,0.0001218975,0.0003429662,0.0001161729,0.0003361771,0.0001862799,0.0002149496,0.0005733281,0.0002301329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000203846,"about_ca_system_score_gemma":0.0001916605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005472017,"about_ca_topic_score_gemma":0.001175128,"domain_scores_codex":[0.9998513,0.00001108252,0.00002029714,0.00004275631,0.000041264,0.00003328233],"domain_scores_gemma":[0.9999039,0.00002050143,0.00002784388,0.00001223253,0.000009016013,0.00002643567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004843486,0.000004808391,0.00008144938,0.00001115179,0.000001169352,0.00002322786,0.00001046606,0.000007752467,0.9996439,0.00001661967,0.000005374839,0.0001457372],"study_design_scores_gemma":[0.00003331853,0.0004455743,0.008815908,0.000005431537,0.00001561458,0.0003797374,0.00007927074,0.0006198197,0.9881111,0.00003907341,0.001447995,0.000007030729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968762,0.0004251152,0.001613624,0.00006056458,0.00002720135,0.00002790099,0.0005428104,0.00002449725,0.0004020576],"genre_scores_gemma":[0.991805,0.000436925,0.004933114,0.00008814189,0.0000154377,0.00008532688,0.001117934,0.00002397473,0.001494247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006309072,"threshold_uncertainty_score":0.0021106,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01078536112112769,"score_gpt":0.2284275888952614,"score_spread":0.2176422277741337,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}