{"id":"W2122680973","doi":"10.1111/jne.12225","title":"Direct Regulation of Gonadotrophin‐Releasing Hormone (GnRH) Transcription By RF‐Amide‐Related Peptide‐3 and Kisspeptin in A Novel GnRH‐Secreting Cell Line, mHypoA‐GnRH/GFP","year":2014,"lang":"en","type":"article","venue":"Journal of Neuroendocrinology","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Kisspeptin; Internal medicine; Endocrinology; Gonadotropin-releasing hormone; Messenger RNA; Hypothalamus; Receptor; Biology; Hormone; Chemistry; Luteinizing hormone; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003086026,0.0003470996,0.001156319,0.0007090407,0.00006675862,0.00001998427,0.0001724432,0.0001351008,0.00002029192],"category_scores_gemma":[0.001032901,0.000322499,0.0002290714,0.0003231763,0.0002420529,0.0002788201,0.00004952221,0.0009007169,0.00000415997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001421435,"about_ca_system_score_gemma":0.0001117776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008888798,"about_ca_topic_score_gemma":0.000006750335,"domain_scores_codex":[0.9966895,0.0003189615,0.001527927,0.0005016512,0.0004357065,0.0005262675],"domain_scores_gemma":[0.9975434,0.0003574639,0.001167919,0.0003501943,0.0004052875,0.0001757586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001445576,0.0003615738,0.004409811,0.00009539773,0.00008481227,0.0001452427,0.0003333658,0.000353418,0.985041,0.00006705637,0.0002436504,0.007419125],"study_design_scores_gemma":[0.01549076,0.00380394,0.8991706,0.0002837419,0.0004828792,0.007294928,0.0002179972,0.004118758,0.06298188,0.0003082622,0.005462667,0.0003835301],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884842,0.004300013,0.001163456,0.004428346,0.0003335662,0.0003738285,0.000007087852,0.00003638859,0.0008731014],"genre_scores_gemma":[0.9961802,0.001342665,0.001457607,0.0001455321,0.0003087382,0.000003963275,0.000009169803,0.00006321528,0.0004888455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9220591,"threshold_uncertainty_score":0.9999227,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01078536112112769,"score_gpt":0.2284275888952614,"score_spread":0.2176422277741337,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}