{"id":"W2122703378","doi":"10.1096/fj.15-272559","title":"TLR5, a novel mediator of innate immunity‐induced osteoclastogenesis and bone loss","year":2015,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Arthritis Research Centre of Canada","funders":"","keywords":"TLR5; RANKL; Osteoclast; Inflammation; Bone remodeling; Flagellin; Immunology; Bone resorption; Arthritis; Osteoprotegerin; TLR4; Receptor; Cell biology; Chemistry; Medicine; Activator (genetics); Biology; Internal medicine; TLR2","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004496151,0.0001029251,0.0001459402,0.0000379598,0.00008704174,0.00002329938,0.000168296,0.00006299212,0.000008580575],"category_scores_gemma":[0.0001835793,0.00006834804,0.00006719375,0.00006822168,0.0001173381,0.000005699124,0.0001296077,0.0001028224,0.000002784715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004600763,"about_ca_system_score_gemma":0.0001733312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000229228,"about_ca_topic_score_gemma":0.000006717199,"domain_scores_codex":[0.9993035,0.00008980779,0.0001947825,0.000095123,0.0001625622,0.0001541952],"domain_scores_gemma":[0.999299,0.00001441253,0.0001399042,0.0002244662,0.0001276224,0.0001946073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002105654,0.00005954667,0.00275778,0.000005978978,0.00004686356,0.000005211663,0.0001410094,0.000006415131,0.9950823,0.00003586814,0.0003149933,0.001333472],"study_design_scores_gemma":[0.001876084,0.0001831903,0.008892992,0.00001315309,0.00009339173,0.0004424248,0.0006405797,0.00001110387,0.9856821,0.0001506512,0.001880303,0.0001340487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941483,0.005036642,0.0001625998,0.000215546,0.0001820128,0.00005297257,0.00003651609,0.000003048011,0.0001623656],"genre_scores_gemma":[0.9989662,0.0003206082,0.0001654347,0.0001450828,0.0002940641,0.000002209254,0.000009827048,0.00001215557,0.00008446677],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009400218,"threshold_uncertainty_score":0.2787152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02331667211046935,"score_gpt":0.2488986052786513,"score_spread":0.225581933168182,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}