{"id":"W2122758063","doi":"10.1016/j.bbamcr.2011.01.028","title":"The TGF-β co-receptor, CD109, promotes internalization and degradation of TGF-β receptors","year":2011,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":136,"is_retracted":false,"has_abstract":false,"ca_institutions":"Polytechnique Montréal; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Internalization; Cell biology; Receptor; Caveolae; Endocytosis; R-SMAD; Signal transduction; Transforming growth factor; SMAD; Biology; Smad2 Protein; TGF alpha; Biochemistry; Growth factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009830914,0.0002963746,0.0002293433,0.000162382,0.0002792301,0.0001169801,0.0007383763,0.000242137,0.00004617781],"category_scores_gemma":[0.000401282,0.0002448024,0.0001587542,0.000344475,0.0005591303,0.00001846968,0.0004026748,0.0003133463,0.00004323092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004727217,"about_ca_system_score_gemma":0.0002524233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008008414,"about_ca_topic_score_gemma":0.00000950991,"domain_scores_codex":[0.9968556,0.00071342,0.000444842,0.0006731639,0.0007434468,0.0005695503],"domain_scores_gemma":[0.9981297,0.0001307781,0.0002673829,0.0007849133,0.0004807464,0.0002064369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003240224,0.0002919738,0.0001620202,0.00008437673,0.0001222414,0.000002059388,0.0002711078,0.000001047568,0.9946077,0.0001403348,0.00284694,0.001146182],"study_design_scores_gemma":[0.0004132375,0.0005539746,0.0004274815,0.00005616573,0.00003174711,0.000001606168,0.0001323412,0.00004006194,0.9905206,0.0001544713,0.007406495,0.0002618096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958389,0.0009177378,0.0004838396,0.0001891991,0.0001240359,0.0005688857,0.00004162083,0.00002749475,0.001808247],"genre_scores_gemma":[0.9966021,0.0007199257,0.0009159677,0.00005883983,0.00009458955,0.00007298683,0.000338665,0.00007354578,0.001123428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004559555,"threshold_uncertainty_score":0.9982752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03994007352225658,"score_gpt":0.3189466125744291,"score_spread":0.2790065390521725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}