{"id":"W2122762460","doi":"10.1002/btpr.1942","title":"Treating cell culture media with UV irradiation against adventitious agents: Minimal impact on CHO performance","year":2014,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Sterilization (economics); Chinese hamster ovary cell; Cell culture; Chemically defined medium; Irradiation; Food science; Cell growth; Cell; Titer; Chemistry; Biology; Biochemistry; Microbiology; In vitro; Immunology; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003458666,0.0005613334,0.000388801,0.0002878392,0.0002979985,0.0006404296,0.0003153416,0.0003875904,0.001015117],"category_scores_gemma":[0.0003569756,0.0001735531,0.0003598639,0.000338272,0.0001970613,0.0003087764,0.0003478009,0.0003873919,0.0004632964],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00023983,"about_ca_system_score_gemma":0.0002841826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009003089,"about_ca_topic_score_gemma":0.001832542,"domain_scores_codex":[0.9996468,0.00006647737,0.0000475454,0.0000778983,0.0001151561,0.00004613183],"domain_scores_gemma":[0.9996942,0.00009695218,0.00007220564,0.00004336027,0.00005853462,0.00003471215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006080408,0.00001236057,0.0001122276,0.00004491791,0.000004614713,0.0000285736,0.0000288618,0.00002032336,0.9988675,0.00001527127,0.00001157442,0.0007929169],"study_design_scores_gemma":[0.000002413935,0.0001004058,0.0008294255,0.000005685011,0.00001679523,0.00005876619,0.00002129995,0.00007478671,0.9977551,0.000007639958,0.001123516,0.000004314441],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856784,0.003507221,0.006925731,0.00009140974,0.0000540855,0.00008278834,0.0005732577,0.000115022,0.002972152],"genre_scores_gemma":[0.9641752,0.004370993,0.02194416,0.0001394314,0.0000210272,0.000196006,0.002396452,0.0001643132,0.006592369],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001015117,"threshold_uncertainty_score":0.003395915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004629796185431096,"score_gpt":0.2374827712890457,"score_spread":0.2328529751036146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}