{"id":"W2122781654","doi":"10.1038/emboj.2008.192","title":"G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription","year":2008,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":422,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"RIKEN; University of British Columbia","keywords":"Biology; DNA methylation; Genetics; Transcription (linguistics); Methylation; DNA; Gene; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003328863,0.0004325428,0.000352271,0.0003581864,0.0005188413,0.0009747396,0.0006787171,0.0005971945,0.006262073],"category_scores_gemma":[0.0004306392,0.0002858418,0.000496429,0.0001373848,0.0006275331,0.000532817,0.001727096,0.001684194,0.002833091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006240984,"about_ca_system_score_gemma":0.000404869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008327898,"about_ca_topic_score_gemma":0.001390918,"domain_scores_codex":[0.9997262,0.00003999318,0.00001029245,0.00008083923,0.00004708036,0.00009564814],"domain_scores_gemma":[0.9997017,0.00004267773,0.00004213171,0.00005332977,0.00003778298,0.0001223755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005290985,0.00003837337,0.0006882953,0.00004529754,0.00003362746,0.0001002987,0.00002051003,0.0001344679,0.9909616,0.001027916,0.000698105,0.005722286],"study_design_scores_gemma":[0.0001305508,0.0002154163,0.007489579,0.00001398303,0.00002187968,0.0001857996,0.0001101694,0.001286679,0.9804878,0.0009643518,0.00908039,0.00001338132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9527181,0.004794765,0.01738553,0.001945055,0.0007779934,0.0001685831,0.001700133,0.0009997552,0.01951002],"genre_scores_gemma":[0.9889465,0.0003317549,0.004248139,0.0003406525,0.00005440437,0.0000466408,0.0009213217,0.0001378404,0.004972957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006262073,"threshold_uncertainty_score":0.02094871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03415816266856176,"score_gpt":0.2754443303754575,"score_spread":0.2412861677068958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}