{"id":"W2122817117","doi":"10.1128/ec.00385-05","title":"Transcript Profiles of <i>Candida albicans</i> Cortical Actin Patch Mutants Reflect Their Cellular Defects: Contribution of the Hog1p and Mkc1p Signaling Pathways","year":2006,"lang":"en","type":"article","venue":"Eukaryotic Cell","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research","keywords":"Biology; Cell biology; Endocytosis; Mutant; Actin; Cytochalasin D; Green fluorescent protein; Osmotic shock; Candida albicans; Signal transduction; Cytoskeleton; Gene; Cell; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000667122,0.0003856191,0.0002020258,0.0005383908,0.0001635397,0.000393694,0.0001590982,0.0002956494,0.0007424459],"category_scores_gemma":[0.0001582907,0.0001725342,0.000283385,0.000410213,0.0001587974,0.0001162899,0.0001628867,0.0004301321,0.0003152397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002842143,"about_ca_system_score_gemma":0.000182132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001867721,"about_ca_topic_score_gemma":0.002165588,"domain_scores_codex":[0.9998431,0.000008153972,0.00001067383,0.00005448596,0.00004221699,0.00004128181],"domain_scores_gemma":[0.9998021,0.00002754208,0.00005858617,0.00001699004,0.00004271997,0.00005217066],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006359845,0.000004645644,0.0006693755,0.00001377247,0.000003012141,0.00003465146,0.00001212242,0.00002329522,0.998614,0.00001723594,0.00002775812,0.0005166649],"study_design_scores_gemma":[0.00001138315,0.0001495823,0.1622447,0.00001614964,0.00003988742,0.0004817436,0.0001816821,0.0009208151,0.8336897,0.00007640923,0.0021612,0.00002673449],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920329,0.0005455134,0.001153204,0.00005042714,0.0000154818,0.00001842722,0.005217542,0.00009734074,0.0008690809],"genre_scores_gemma":[0.9854354,0.0004668882,0.00229207,0.0001082688,0.00001307572,0.00008514172,0.008709944,0.00007390844,0.00281535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001867721,"threshold_uncertainty_score":0.003713667,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01075490999147765,"score_gpt":0.2159272975852814,"score_spread":0.2051723875938037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}