{"id":"W2122817117","doi":"10.1128/ec.00385-05","title":"Transcript Profiles of <i>Candida albicans</i> Cortical Actin Patch Mutants Reflect Their Cellular Defects: Contribution of the Hog1p and Mkc1p Signaling Pathways","year":2006,"lang":"en","type":"article","venue":"Eukaryotic Cell","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research","keywords":"Biology; Cell biology; Endocytosis; Mutant; Actin; Cytochalasin D; Green fluorescent protein; Osmotic shock; Candida albicans; Signal transduction; Cytoskeleton; Gene; Cell; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004487682,0.0001954847,0.0004984325,0.00003735964,0.0001032181,0.000008848068,0.0001075113,0.0001296972,0.00008444041],"category_scores_gemma":[0.000129522,0.0001271572,0.0002001363,0.0002328231,0.0003061649,0.00004824858,0.00002665005,0.0002797274,0.000001940549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005383333,"about_ca_system_score_gemma":0.0001610844,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000252165,"about_ca_topic_score_gemma":0.000120354,"domain_scores_codex":[0.998367,0.0001370529,0.0005283295,0.0003044704,0.0003512301,0.0003119709],"domain_scores_gemma":[0.9989377,0.0002629831,0.0001938645,0.0003617569,0.0001582398,0.00008548953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003429355,0.0002516053,0.3316254,0.0002417915,0.00001839269,0.00001108835,0.0001770549,0.000003113806,0.6668866,0.0001696498,0.0000569341,0.0002154784],"study_design_scores_gemma":[0.001075038,0.0002475716,0.297857,0.0001785487,0.0001450337,0.000005177337,0.000307784,0.0001016127,0.6996647,0.0002855357,0.0000399419,0.00009214893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955891,0.001383344,0.000759333,0.00009829486,0.00009393032,0.0006235073,0.00007416538,0.00002446619,0.001353801],"genre_scores_gemma":[0.999488,0.000052575,0.00009641189,0.00007079944,0.00006392391,0.000006925663,0.0000293215,0.00001922366,0.0001728246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03376846,"threshold_uncertainty_score":0.5185321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01075490999147765,"score_gpt":0.2159272975852814,"score_spread":0.2051723875938037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}