{"id":"W2122870515","doi":"10.1136/thoraxjnl-2013-204778","title":"Lessons from ECLIPSE: a review of COPD biomarkers","year":2013,"lang":"en","type":"review","venue":"Thorax","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":166,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"GlaxoSmithKline","keywords":"Eclipse; COPD; Medicine; Biomarker; Pulmonary disease; Government (linguistics); Observational study; Intensive care medicine; Medical physics; Family medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0005686448,0.0006446381,0.003968569,0.0003068018,0.00005501818,0.00001965437,0.0006052929,0.0003960475,0.01717109],"category_scores_gemma":[0.0004901041,0.000488643,0.001278516,0.0008627989,0.0003786802,0.00008732719,0.0003699363,0.0007582291,0.002145726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005899486,"about_ca_system_score_gemma":0.002086005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002511237,"about_ca_topic_score_gemma":0.000003459662,"domain_scores_codex":[0.9959257,0.0005501995,0.001173227,0.0008429544,0.0009265076,0.0005814599],"domain_scores_gemma":[0.9963011,0.0004337111,0.0006277304,0.001763969,0.0003366556,0.0005368123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001362581,0.00009999267,0.000007468135,0.3092868,0.0006580502,0.00009101239,0.000005441237,2.353817e-9,0.000001520788,0.00006707382,0.04303615,0.6467328],"study_design_scores_gemma":[0.0002683336,0.00003358281,0.00009395745,0.27389,0.002932952,0.00005401119,0.00001255244,0.000002428248,0.000001503275,0.00006384328,0.7223741,0.0002727112],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00000718746,0.9795107,0.000005149329,0.0006006838,0.000318508,0.00380236,0.00136806,0.00006027782,0.01432705],"genre_scores_gemma":[9.273633e-7,0.992118,0.0005105372,0.0001580942,0.0008833564,0.0004244555,0.001827123,0.0001395166,0.003937974],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6793379,"threshold_uncertainty_score":0.9997565,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09566041097925614,"score_gpt":0.426323529700152,"score_spread":0.3306631187208959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}