{"id":"W2122994980","doi":"10.2337/dc09-2294","title":"A 24-Week, Randomized, Treat-to-Target Trial Comparing Initiation of Insulin Glargine Once-Daily With Insulin Detemir Twice-Daily in Patients With Type 2 Diabetes Inadequately Controlled on Oral Glucose-Lowering Drugs","year":2010,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":158,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McMaster University Medical Centre; LMC Diabetes & Endocrinology (Canada)","funders":"European Foundation for the Study of Diabetes; Novo Nordisk; Sanofi","keywords":"Medicine; Insulin glargine; Insulin detemir; Hypoglycemia; Internal medicine; Diabetes mellitus; Type 2 diabetes; Randomized controlled trial; Endocrinology; Insulin; Type 1 diabetes; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002045069,0.001871265,0.004704243,0.0006941768,0.00041684,0.001303783,0.00125513,0.001934865,0.005424306],"category_scores_gemma":[0.003365592,0.0007332186,0.00178636,0.0005276335,0.001257941,0.001215338,0.0005337697,0.002897111,0.0009195248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006639181,"about_ca_system_score_gemma":0.0008283826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006438823,"about_ca_topic_score_gemma":0.001117868,"domain_scores_codex":[0.9987743,0.0007918745,0.0000600173,0.0001886833,0.0000729129,0.000112146],"domain_scores_gemma":[0.9976172,0.0008821088,0.0005510436,0.0001720445,0.00008606116,0.0006914573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9886268,0.004839492,0.0002449543,0.0001618458,0.000332006,0.00001987521,0.00002437694,0.0001919279,0.0007189932,0.000027248,0.0001932616,0.004619232],"study_design_scores_gemma":[0.9628481,0.03545853,0.0008953678,0.00001121988,0.0001534657,0.00002077362,0.00001257472,0.0002918135,0.0001370271,0.00006386617,0.0000995283,0.000007710944],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946119,0.001828506,0.0003538133,0.0004209022,0.0003056435,0.001239704,0.0003500786,0.0001011438,0.0007883396],"genre_scores_gemma":[0.991461,0.001187569,0.001547408,0.0008026113,0.0004448906,0.002244841,0.0005559,0.00003117224,0.001724558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005424306,"threshold_uncertainty_score":0.01814616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.010673327803946,"score_gpt":0.2297990433556527,"score_spread":0.2191257155517067,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}