{"id":"W2123002291","doi":"10.1016/j.ejcts.2004.04.037","title":"Inhibition of inducible nitric oxide synthase and superoxide production reduces matrix metalloproteinase-9 activity and restores coronary vasomotor function in rat cardiac allografts","year":2004,"lang":"en","type":"article","venue":"European Journal of Cardio-Thoracic Surgery","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Superoxide; Nitric oxide; Nitric oxide synthase; Vasomotor; Nitrotyrosine; Superoxide dismutase; Chemistry; Endothelium; Matrix metalloproteinase; Pharmacology; Internal medicine; Endocrinology; Medicine; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006362522,0.0002183369,0.0008361661,0.000767572,0.00007422174,0.00002615125,0.00003605597,0.00006444834,0.000004543133],"category_scores_gemma":[0.0006541499,0.0001862124,0.0002881725,0.0004455052,0.0001405837,0.0005600779,0.00002226354,0.0003778265,0.000001053345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009652392,"about_ca_system_score_gemma":0.0001758015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003962231,"about_ca_topic_score_gemma":0.000002632008,"domain_scores_codex":[0.9965947,0.00172209,0.0007222361,0.0002954185,0.0004470132,0.0002184931],"domain_scores_gemma":[0.998647,0.0003133682,0.0004322214,0.0001995347,0.0002238251,0.0001839935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003572116,0.0001580308,0.1286391,0.0004669805,0.0003233484,0.001428487,0.0003173304,0.0001292029,0.8082687,0.000005438528,0.00004036948,0.05665085],"study_design_scores_gemma":[0.000616385,0.0002294419,0.7065338,0.0007978978,0.0004902692,0.001279873,0.0003113851,5.684759e-7,0.2894186,0.00004152038,0.0001309636,0.0001493433],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992696,0.005430607,0.0006554534,0.0003105408,0.0005017486,0.000317988,0.000008336216,0.00002271869,0.00005654975],"genre_scores_gemma":[0.9928046,0.002687066,0.004099093,0.00001909922,0.0003067795,0.000004529197,0.000008700675,0.00003918864,0.00003096406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5778947,"threshold_uncertainty_score":0.7593523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03327202061384194,"score_gpt":0.2946898688325321,"score_spread":0.2614178482186902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}