{"id":"W2123027910","doi":"10.1200/jco.2012.43.8820","title":"Randomized Phase III Trial of Induction Chemotherapy With Docetaxel, Cisplatin, and Fluorouracil Followed by Surgery Versus Up-Front Surgery in Locally Advanced Resectable Oral Squamous Cell Carcinoma","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":391,"is_retracted":false,"has_abstract":true,"ca_institutions":"CAE (Canada)","funders":"Science and Technology Commission of Shanghai Municipality; National Natural Science Foundation of China; Sanofi","keywords":"Medicine; Docetaxel; Induction chemotherapy; Chemotherapy; Surgery; Radiation therapy; Fluorouracil; Perioperative; Cisplatin; Radical surgery; Clinical endpoint; Urology; Internal medicine; Randomized controlled trial; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01002858,0.0002182196,0.004776565,0.0002181659,0.00004361193,0.000005513504,0.00006449319,0.0003561047,0.00008026329],"category_scores_gemma":[0.005556929,0.0001429204,0.000539948,0.0001944118,0.0003424603,0.0002723401,0.00002472462,0.0007750468,0.000001035116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001620846,"about_ca_system_score_gemma":0.001614127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001153875,"about_ca_topic_score_gemma":0.00009251352,"domain_scores_codex":[0.9948277,0.0009874589,0.003108031,0.0002091899,0.0004507205,0.0004168493],"domain_scores_gemma":[0.9857952,0.01104318,0.002241606,0.0001661152,0.0003786429,0.0003752369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9144751,0.003020806,0.01108027,0.00006152297,0.0002173704,0.00008482365,0.0003231467,0.000001842305,0.0006338483,0.000001367513,0.01340348,0.05669637],"study_design_scores_gemma":[0.9709976,0.01644454,0.003040292,0.0001122634,0.0004479545,0.00007211471,0.0003659843,0.00002627618,0.001498155,0.000006560078,0.006835433,0.000152822],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892803,0.004327216,0.00007222555,0.001777945,0.003124657,0.000614705,0.000003089012,0.000006767083,0.0007931003],"genre_scores_gemma":[0.9956951,0.002350277,0.0005634793,0.0002923258,0.0008042075,0.00002302922,0.000004616329,0.00002333208,0.000243611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05654355,"threshold_uncertainty_score":0.6652564,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1137993340792427,"score_gpt":0.4290821510197088,"score_spread":0.3152828169404661,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}