{"id":"W2123035617","doi":"10.1016/j.ccr.2011.12.021","title":"An Animal Model of MYC-Driven Medulloblastoma","year":2012,"lang":"en","type":"article","venue":"Cancer Cell","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":317,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Cancer Institute","keywords":"Medulloblastoma; Cancer research; Stem cell; Biology; PI3K/AKT/mTOR pathway; Transplantation; Sonic hedgehog; Oncogene; Signal transduction; Medicine; Cell biology; Cell; Genetics; Internal medicine; Cell cycle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003009489,0.00008523116,0.0001681476,0.00002375807,0.0000173862,0.000002503573,0.0000429422,0.00004282785,0.0003556988],"category_scores_gemma":[0.000001922839,0.00006736023,0.00005700314,0.00004712155,0.00002621826,0.00008797286,0.00001255609,0.00003666555,0.00002166168],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000885194,"about_ca_system_score_gemma":0.00005427341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001579061,"about_ca_topic_score_gemma":0.00003101876,"domain_scores_codex":[0.9994602,0.000008315348,0.0001080971,0.0001080975,0.0001235209,0.0001917945],"domain_scores_gemma":[0.9995154,0.000008516134,0.00004605191,0.000197569,0.00004402287,0.000188398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002387804,0.00254979,0.3787032,0.0001499294,0.0001018186,0.00001233945,0.001553993,0.001407667,0.6074436,0.0005287234,0.003904618,0.003405539],"study_design_scores_gemma":[0.002933624,0.0008366691,0.08243054,0.00008619625,0.0003865185,0.000009140909,0.0002514597,0.02458374,0.8860024,0.00002247872,0.002265785,0.0001914054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920341,0.002489984,0.00004119677,0.0001215851,0.00008115453,0.0001385196,0.00002581517,0.00001992947,0.005047733],"genre_scores_gemma":[0.9980661,0.0001828447,0.001270609,0.000148862,0.0001435127,0.00004649204,0.000008514236,0.00001616167,0.0001168638],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2962727,"threshold_uncertainty_score":0.3894653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02755345535867589,"score_gpt":0.3010216191921951,"score_spread":0.2734681638335192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}