{"id":"W2123035617","doi":"10.1016/j.ccr.2011.12.021","title":"An Animal Model of MYC-Driven Medulloblastoma","year":2012,"lang":"en","type":"article","venue":"Cancer Cell","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":317,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Cancer Institute","keywords":"Medulloblastoma; Cancer research; Stem cell; Biology; PI3K/AKT/mTOR pathway; Transplantation; Sonic hedgehog; Oncogene; Signal transduction; Medicine; Cell biology; Cell; Genetics; Internal medicine; Cell cycle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000460959,0.000893974,0.0005276946,0.00168355,0.00077587,0.0005274073,0.0009312783,0.001419896,0.003526656],"category_scores_gemma":[0.0002718183,0.0004482114,0.0005158296,0.0004304808,0.001099235,0.000702788,0.0004154431,0.002048999,0.0009205429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001222331,"about_ca_system_score_gemma":0.0007061812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002219808,"about_ca_topic_score_gemma":0.005329374,"domain_scores_codex":[0.9996314,0.00005933428,0.00003307783,0.00008553577,0.0001242198,0.00006646024],"domain_scores_gemma":[0.9996015,0.00009117424,0.00009987485,0.00006871686,0.00002611085,0.0001126199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001450808,0.001123303,0.0008621836,0.0001310548,0.00005939231,0.001267385,0.0001246685,0.0007587973,0.9829321,0.006042662,0.001261197,0.003986456],"study_design_scores_gemma":[0.0006094401,0.005724238,0.003494406,0.0000643504,0.0002017644,0.004265785,0.0002197446,0.005964784,0.9495729,0.001813142,0.02801717,0.00005231691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9692168,0.002343391,0.01381189,0.002062371,0.0005544855,0.0005185364,0.002969703,0.000620466,0.007902425],"genre_scores_gemma":[0.9652043,0.001948436,0.01268529,0.0002912808,0.00006528811,0.0004555512,0.001412906,0.0001102924,0.01782668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003526656,"threshold_uncertainty_score":0.01179785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02755345535867589,"score_gpt":0.3010216191921951,"score_spread":0.2734681638335192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}