{"id":"W2123042478","doi":"10.1038/sj.cdd.4402050","title":"Genetic variance modifies apoptosis susceptibility in mature oocytes via alterations in DNA repair capacity and mitochondrial ultrastructure","year":2006,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; Lunenfeld-Tanenbaum Research Institute; Ontario Institute for Cancer Research; University of Toronto; Mount Sinai Hospital","funders":"National Center for Research Resources; Canadian Institutes of Health Research; College of Engineering, Michigan State University; National Institute on Aging; National Institutes of Health; Michigan State University","keywords":"Biology; Apoptosis; Microinjection; Mitochondrial DNA; Mitochondrion; Cell biology; DNA damage; Programmed cell death; Genetics; Embryonic stem cell; Molecular biology; Gene; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003024066,0.0002800064,0.000371226,0.0008582838,0.0002473298,0.0003441393,0.0003604577,0.000462847,0.00346255],"category_scores_gemma":[0.0007771153,0.0002326504,0.0002276801,0.0003853301,0.0003586843,0.0001859894,0.0002952157,0.0005763969,0.0001992618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003165175,"about_ca_system_score_gemma":0.0002167614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000833494,"about_ca_topic_score_gemma":0.001081623,"domain_scores_codex":[0.9994953,0.0001412768,0.00004861098,0.0001574849,0.00008424397,0.00007313104],"domain_scores_gemma":[0.9991763,0.000272171,0.0002389153,0.00008978365,0.00006677514,0.0001559909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001366752,0.0001162709,0.006126835,0.00002005568,0.00007638957,0.000165843,0.00008536987,0.0000741789,0.9903722,0.0002733957,0.00003406213,0.001288581],"study_design_scores_gemma":[0.0002747043,0.002134551,0.6001176,0.00003167812,0.0005409486,0.00249695,0.0004169369,0.003562836,0.3876401,0.001120877,0.001579237,0.00008350714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989204,0.00008052555,0.0006096664,0.00003119799,0.00001014088,0.000006281606,0.0001250735,0.00001812198,0.0001986492],"genre_scores_gemma":[0.9985789,0.00006322951,0.0005245368,0.00001768395,0.000006152378,0.000009191512,0.000112991,0.00003201847,0.0006552041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00346255,"threshold_uncertainty_score":0.01158339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00968407060080099,"score_gpt":0.2164117532800686,"score_spread":0.2067276826792676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}