{"id":"W2123063574","doi":"10.1074/jbc.m402787200","title":"Bioengineering of Surface GD3 Ganglioside for Immunotargeting Human Melanoma Cells","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Keyhole limpet hemocyanin; Hemocyanin; Immunogenicity; Sialic acid; Monoclonal antibody; Molecular biology; Epitope; Immunogen; Chemistry; Antigen; Ganglioside; Antiserum; Polysialic acid; Biochemistry; Polyclonal antibodies; Biology; Antibody; Cell; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000110375,0.0003264855,0.0001313378,0.0001571171,0.00009468293,0.0001653662,0.0001336639,0.0001861288,0.0004826659],"category_scores_gemma":[0.00006839618,0.00009773023,0.0002064713,0.0001233666,0.00007321545,0.00006474915,0.0001939541,0.0002612277,0.0003995076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002588678,"about_ca_system_score_gemma":0.0002464033,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00107539,"about_ca_topic_score_gemma":0.001567903,"domain_scores_codex":[0.9999388,0.00001117605,0.000003722262,0.00001025411,0.00001953246,0.00001646823],"domain_scores_gemma":[0.9999783,0.000002576176,0.000004277363,0.000003951634,0.000005299144,0.000005577009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001289389,0.000007486339,0.00004014701,0.000009591642,0.00000104546,0.00001673144,0.000006331073,0.0000567907,0.9993312,0.00003761022,0.00001047829,0.0004697533],"study_design_scores_gemma":[0.000008380431,0.00013032,0.0007017063,0.000004467518,0.000007956717,0.0001500527,0.00001174068,0.0007103293,0.9958357,0.0000380714,0.00239916,0.000002094123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9794796,0.001763662,0.01517828,0.0001176565,0.00003641323,0.0001529159,0.0003016986,0.000121232,0.002848506],"genre_scores_gemma":[0.9852446,0.001206781,0.01098728,0.00005864224,0.000006545999,0.00007570863,0.0004820484,0.00002091745,0.001917336],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00107539,"threshold_uncertainty_score":0.002138257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01917549176446152,"score_gpt":0.2760466931707718,"score_spread":0.2568712014063103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}