{"id":"W2123070344","doi":"10.1002/jcb.10294","title":"14‐3‐3σ is a cruciform DNA binding protein and associates in vivo with origins of DNA replication","year":2002,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Molecular biology; Cruciform; Biology; Origin recognition complex; DNA replication; Control of chromosome duplication; Eukaryotic DNA replication; Chromatin immunoprecipitation; DNA; S phase; Immunoprecipitation; Chromatin; Western blot; Replication factor C; Cell biology; Antibody; Biochemistry; Gene; Gene expression; Genetics; Promoter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001387848,0.0004949588,0.0003513103,0.0003154616,0.000387737,0.0004000381,0.0003139835,0.0003025944,0.001231291],"category_scores_gemma":[0.0001794439,0.0003431654,0.000453013,0.0003106247,0.0002852883,0.0001971527,0.0004041818,0.0004899412,0.0007184606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005713563,"about_ca_system_score_gemma":0.0003388442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001473477,"about_ca_topic_score_gemma":0.001566327,"domain_scores_codex":[0.9997526,0.00002049183,0.0000132134,0.00008514796,0.00008592552,0.00004262808],"domain_scores_gemma":[0.9998364,0.00002172231,0.00005699851,0.00002142199,0.00002470689,0.00003871748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005221417,0.000007424262,0.0007348019,0.00001909961,0.000005323921,0.00003469071,0.00001254416,0.00001563285,0.9983587,0.00003876396,0.00001555963,0.0007052417],"study_design_scores_gemma":[0.000007908516,0.000108275,0.02772509,0.000007209369,0.00001260367,0.0004375753,0.00003170532,0.0003309622,0.9671841,0.00006976689,0.004077862,0.00000701365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892266,0.002769819,0.006220283,0.00006616375,0.00002315339,0.0000245075,0.0003699708,0.0001387232,0.001160872],"genre_scores_gemma":[0.9872435,0.00111904,0.004949559,0.00004695753,0.00001646316,0.00003388782,0.001811117,0.00003892418,0.004740614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001473477,"threshold_uncertainty_score":0.004145503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00887172308136319,"score_gpt":0.2314532852254907,"score_spread":0.2225815621441275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}