{"id":"W2123070344","doi":"10.1002/jcb.10294","title":"14‐3‐3σ is a cruciform DNA binding protein and associates in vivo with origins of DNA replication","year":2002,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Molecular biology; Cruciform; Biology; Origin recognition complex; DNA replication; Control of chromosome duplication; Eukaryotic DNA replication; Chromatin immunoprecipitation; DNA; S phase; Immunoprecipitation; Chromatin; Western blot; Replication factor C; Cell biology; Antibody; Biochemistry; Gene; Gene expression; Genetics; Promoter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002828915,0.0001564041,0.0002249685,0.00008523938,0.00004334539,0.00002592676,0.000180851,0.0001977278,0.00008148556],"category_scores_gemma":[0.0001877344,0.0001386691,0.00009573444,0.0001505727,0.00007883114,0.00001466472,0.0000477629,0.0002133657,0.000001659845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001072114,"about_ca_system_score_gemma":0.00006641151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001090116,"about_ca_topic_score_gemma":0.000004199916,"domain_scores_codex":[0.9988543,0.00002627459,0.0004640652,0.0002522838,0.0002220305,0.0001810714],"domain_scores_gemma":[0.9986712,0.00001241996,0.0006536855,0.0003497047,0.0002272449,0.00008577601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006868198,0.000124163,0.002072426,0.00007217207,0.0000780744,0.00001058969,0.00007371801,0.000001224043,0.9967431,0.000007100738,0.000531628,0.0002170548],"study_design_scores_gemma":[0.0006651833,0.0002558466,0.00006508826,0.0002208917,0.00002837008,0.0001208562,0.000123206,0.00001956147,0.9952697,0.00002476788,0.00305686,0.0001496926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997964,0.000742143,0.0001468542,0.0002760395,0.00003160185,0.0001497468,0.00002160433,0.000003486255,0.0006645657],"genre_scores_gemma":[0.9969675,0.0001437291,0.001094904,0.00002660575,0.0001323308,0.00001162332,0.000008445935,0.00002098871,0.00159386],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002525232,"threshold_uncertainty_score":0.5654763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00887172308136319,"score_gpt":0.2314532852254907,"score_spread":0.2225815621441275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}