{"id":"W2123098020","doi":"10.1158/1078-0432.ccr-07-0944","title":"Treatment of Hormone-Refractory Prostate Cancer with Docetaxel or Mitoxantrone: Relationships between Prostate-Specific Antigen, Pain, and Quality of Life Response and Survival in the TAX-327 Study","year":2008,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":208,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Medicine; Mitoxantrone; Docetaxel; Prostate cancer; Quality of life (healthcare); Internal medicine; Oncology; Prostate-specific antigen; Cancer; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01222182,0.000264557,0.001080776,0.0002972217,0.0003420563,0.00002786835,0.0001910415,0.0001661124,0.00003200478],"category_scores_gemma":[0.001763514,0.000135958,0.00008800577,0.0009774604,0.002150425,0.0001272063,0.00009560067,0.0009623769,0.000001575416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000281526,"about_ca_system_score_gemma":0.002331143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004827663,"about_ca_topic_score_gemma":0.002252488,"domain_scores_codex":[0.9891401,0.006870301,0.001203021,0.0007115955,0.001449557,0.0006254329],"domain_scores_gemma":[0.9896446,0.008352424,0.0002623546,0.0006470713,0.0007119,0.000381612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.09327546,0.002130682,0.8872709,0.0001362177,0.0003229396,0.0001358627,0.008484083,0.0000020724,0.0006045346,0.000005885875,0.0003570818,0.007274287],"study_design_scores_gemma":[0.01617572,0.01989449,0.9531374,0.0001179112,0.00005073933,0.000003135874,0.007784576,0.00000859265,0.000127899,0.00001246187,0.002542216,0.0001448686],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9647816,0.02733747,0.000001629683,0.003595945,0.00003343957,0.003950043,0.0002510324,0.0000131997,0.00003566539],"genre_scores_gemma":[0.9236792,0.07447403,0.00004517327,0.0000177525,0.0001589293,0.0007264551,0.00002040889,0.00003377639,0.0008442825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07709973,"threshold_uncertainty_score":0.7923331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4838946235681214,"score_gpt":0.5233336333598677,"score_spread":0.0394390097917463,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}