{"id":"W2123098020","doi":"10.1158/1078-0432.ccr-07-0944","title":"Treatment of Hormone-Refractory Prostate Cancer with Docetaxel or Mitoxantrone: Relationships between Prostate-Specific Antigen, Pain, and Quality of Life Response and Survival in the TAX-327 Study","year":2008,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":208,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Medicine; Mitoxantrone; Docetaxel; Prostate cancer; Quality of life (healthcare); Internal medicine; Oncology; Prostate-specific antigen; Cancer; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003572766,0.0004028103,0.0007704525,0.0002260386,0.0001729971,0.000637177,0.0003805888,0.0005351247,0.001230064],"category_scores_gemma":[0.002339388,0.000244129,0.001146752,0.0003170058,0.0005347079,0.0003278277,0.0002549607,0.0008421122,0.0001460293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004808157,"about_ca_system_score_gemma":0.0006144699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009061257,"about_ca_topic_score_gemma":0.001351923,"domain_scores_codex":[0.9987825,0.000923908,0.000058412,0.00007238857,0.00009355751,0.00006921524],"domain_scores_gemma":[0.9977696,0.0008396574,0.000726028,0.0001890732,0.00006249058,0.000413272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6296282,0.01164623,0.3177463,0.0005117452,0.004965172,0.0001410884,0.0001391436,0.002180254,0.003854215,0.0001696951,0.001232817,0.02778515],"study_design_scores_gemma":[0.1783092,0.1614399,0.6451871,0.0001407362,0.004275213,0.0004589256,0.0001580967,0.004986475,0.002097963,0.0003667064,0.002515088,0.00006445708],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998793,0.0006615549,0.00005790633,0.0000640248,0.00001305103,0.00007090598,0.000191354,0.000003165448,0.0001450464],"genre_scores_gemma":[0.9984949,0.0003718784,0.0001091318,0.00009189436,0.00004172348,0.00007559853,0.0005847114,0.000001643408,0.000228586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003572766,"threshold_uncertainty_score":0.01889479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4838946235681214,"score_gpt":0.5233336333598677,"score_spread":0.0394390097917463,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}