{"id":"W2123111197","doi":"10.2337/db12-1203","title":"Linking the Metabolic State and Mitochondrial DNA in Chronic Disease, Health, and Aging","year":2013,"lang":"en","type":"article","venue":"Diabetes","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research; Medical Research Council; National Institute for Health and Care Research; Wellcome Trust","keywords":"Mitochondrial DNA; Disease; Chronic disease; Medicine; Biology; Bioinformatics; Gerontology; Genetics; Intensive care medicine; Internal medicine; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008619989,0.00009482993,0.0001166798,0.00003277666,0.00008333316,0.00004349391,0.00006027126,0.00004186207,0.00002118088],"category_scores_gemma":[0.0000512293,0.0000702649,0.00002347862,0.00004847613,0.00007877077,0.000005433409,0.00007152351,0.00007931691,0.000009510289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006137354,"about_ca_system_score_gemma":0.00006987264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002885768,"about_ca_topic_score_gemma":0.00005113536,"domain_scores_codex":[0.9992588,0.0001062247,0.0001314,0.0002282863,0.00004494258,0.0002303225],"domain_scores_gemma":[0.9996502,0.00002508071,0.00004287894,0.0001536761,0.00001710802,0.0001110763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002257226,0.00001875567,0.07518787,0.00006480712,0.00003016977,0.000001035937,0.0003477747,0.0000183614,0.8779708,0.0002099765,0.001635193,0.04449266],"study_design_scores_gemma":[0.004970598,0.0009092583,0.250899,0.0002153934,0.00005896392,0.000009969301,0.0003571546,0.001833064,0.1701236,0.005717289,0.56381,0.001095659],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.976051,0.02216143,0.00005177322,0.001132692,0.0002856369,0.0002471511,0.000006584452,0.000005641488,0.00005806448],"genre_scores_gemma":[0.9940268,0.002465278,0.0001945198,0.002080895,0.0005971801,0.00008715721,0.00005656275,0.00001574176,0.0004759049],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7078472,"threshold_uncertainty_score":0.286532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008387502306670966,"score_gpt":0.2377654934134986,"score_spread":0.2293779911068277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}