{"id":"W2123164802","doi":"10.1371/journal.pgen.1001378","title":"GWAS of Follicular Lymphoma Reveals Allelic Heterogeneity at 6p21.32 and Suggests Shared Genetic Susceptibility with Diffuse Large B-cell Lymphoma","year":2011,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":105,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Canada's Michael Smith Genome Sciences Centre; Simon Fraser University; Burnaby Hospital; BC Cancer Agency","funders":"National Institute of Environmental Health Sciences; Cancer Council NSW; National Health and Medical Research Council; Medical Research Council; Canadian Institutes of Health Research; AFA Försäkring; Michael Smith Health Research BC; Genome Institute of Singapore; National Cancer Institute; Sundhed og Sygdom, Det Frie Forskningsråd; Cancerfonden; National Institutes of Health; Vetenskapsrådet; Yale University","keywords":"Biology; Follicular lymphoma; Allele; Genome-wide association study; Genetics; Diffuse large B-cell lymphoma; Lymphoma; Genetic heterogeneity; Phenotype; Single-nucleotide polymorphism; Genotype; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001351994,0.0004800456,0.0008013624,0.000105272,0.000128614,0.00002126849,0.0001920754,0.0002226773,0.00013468],"category_scores_gemma":[0.00003614996,0.0003729391,0.0001956506,0.0001899093,0.000201824,0.00004491635,0.0002604646,0.00004272052,0.00004645121],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002798645,"about_ca_system_score_gemma":0.0001405635,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008751645,"about_ca_topic_score_gemma":0.000365464,"domain_scores_codex":[0.997312,0.0001195297,0.0006036438,0.0007932418,0.0005563112,0.0006152797],"domain_scores_gemma":[0.997726,0.00007871238,0.0002688724,0.001198537,0.0002365091,0.0004913224],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000499011,0.01543394,0.961831,0.0004607739,0.0005071475,0.0003084253,0.0009252729,0.000001437527,0.01816568,0.000009581073,0.0001789543,0.001678724],"study_design_scores_gemma":[0.01842772,0.001492079,0.7007994,0.0001280889,0.0007854314,0.0001360804,0.00004762011,0.0002035463,0.2773275,0.00003957843,0.000301252,0.0003117015],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918905,0.006155702,0.00001197302,0.00004346265,0.0000443426,0.001123745,0.0001677145,0.00006597982,0.0004965201],"genre_scores_gemma":[0.9940426,0.001300404,0.003943223,0.0002377911,0.00005699359,0.0001155562,0.00008116695,0.00007989444,0.0001424238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2610317,"threshold_uncertainty_score":0.9998723,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.027678270282106,"score_gpt":0.2371966895946567,"score_spread":0.2095184193125507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}