{"id":"W2123164802","doi":"10.1371/journal.pgen.1001378","title":"GWAS of Follicular Lymphoma Reveals Allelic Heterogeneity at 6p21.32 and Suggests Shared Genetic Susceptibility with Diffuse Large B-cell Lymphoma","year":2011,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":105,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Canada's Michael Smith Genome Sciences Centre; Simon Fraser University; Burnaby Hospital; BC Cancer Agency","funders":"National Institute of Environmental Health Sciences; Cancer Council NSW; National Health and Medical Research Council; Medical Research Council; Canadian Institutes of Health Research; AFA Försäkring; Michael Smith Health Research BC; Genome Institute of Singapore; National Cancer Institute; Sundhed og Sygdom, Det Frie Forskningsråd; Cancerfonden; National Institutes of Health; Vetenskapsrådet; Yale University","keywords":"Biology; Follicular lymphoma; Allele; Genome-wide association study; Genetics; Diffuse large B-cell lymphoma; Lymphoma; Genetic heterogeneity; Phenotype; Single-nucleotide polymorphism; Genotype; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006619605,0.0005498404,0.0005868549,0.0008915705,0.0003561263,0.0006805666,0.0004503049,0.0006202183,0.00286865],"category_scores_gemma":[0.002123671,0.0002744193,0.0007233084,0.001673957,0.0004409222,0.0001930125,0.0006311761,0.0006372523,0.0003472607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001849434,"about_ca_system_score_gemma":0.000129949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002301231,"about_ca_topic_score_gemma":0.002113449,"domain_scores_codex":[0.9991633,0.0002218665,0.00007350327,0.0003508816,0.0001280966,0.00006250713],"domain_scores_gemma":[0.9990221,0.0002785973,0.0003610626,0.0001654431,0.0000561238,0.0001166667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002988328,0.00006992735,0.9093429,0.0001501811,0.002081983,0.002165825,0.0003925288,0.0006762439,0.0586171,0.0005303664,0.001203188,0.02178152],"study_design_scores_gemma":[0.00008274988,0.0001666785,0.9941254,0.00001075837,0.0004162957,0.00236322,0.00008968035,0.0006094932,0.0008213352,0.0004210866,0.0008808365,0.0000124019],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970867,0.00106223,0.0008078947,0.00009207534,0.00001233404,0.000008068013,0.0004527621,0.00007058834,0.0004072979],"genre_scores_gemma":[0.998795,0.0001940734,0.0004092642,0.0000359334,0.00001891166,0.000005533991,0.000379513,0.00001081783,0.0001508813],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00286865,"threshold_uncertainty_score":0.009596586,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.027678270282106,"score_gpt":0.2371966895946567,"score_spread":0.2095184193125507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}