{"id":"W2123240514","doi":"10.1101/gad.1485307","title":"<i>Rb</i> is critical in a mammalian tissue stem cell population","year":2007,"lang":"en","type":"article","venue":"Genes & Development","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Science Foundation; National Institutes of Health; National Cancer Institute; National Institute of Biomedical Imaging and Bioengineering; Leukemia and Lymphoma Society","keywords":"Biology; Cell biology; Trophoblast; Population; Stem cell; Embryonic stem cell; Ectopic expression; Neural stem cell; Cancer research; Fetus; Genetics; Placenta; Cell culture; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004298439,0.0001293897,0.0001012363,0.00006719409,0.0000611721,0.00001875273,0.0000928899,0.0001436866,0.00002317604],"category_scores_gemma":[0.000008685638,0.0001373157,0.00002546953,0.0000990441,0.00001760253,0.000002989504,0.00006592655,0.00004872452,0.00003086997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000373399,"about_ca_system_score_gemma":0.00005467627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000306488,"about_ca_topic_score_gemma":0.0001994202,"domain_scores_codex":[0.9988962,0.00002943964,0.0003216773,0.0003020137,0.0001602641,0.0002903562],"domain_scores_gemma":[0.9996297,0.00001209215,0.00004289477,0.0001748785,0.00005390128,0.00008657362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003543912,0.00008412883,0.06321564,0.00003944424,0.000007270172,0.00001076398,0.0003131066,0.00003877672,0.7296362,0.00008193993,0.0001413759,0.2063959],"study_design_scores_gemma":[0.0001855513,0.00004435872,0.08680574,0.000006908007,0.000003145091,0.000001266637,0.00007392099,0.000005263155,0.8059057,0.0000560116,0.1067468,0.0001653564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858003,0.002722695,0.009428427,0.000107564,0.0001807369,0.0001445697,0.000002823739,0.0000082455,0.001604607],"genre_scores_gemma":[0.9875152,0.0001482604,0.01111557,0.0002095374,0.0001212974,0.00001168764,0.00009425478,0.00001819155,0.0007660406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2062306,"threshold_uncertainty_score":0.559957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01246775969972474,"score_gpt":0.278586120279472,"score_spread":0.2661183605797473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}