{"id":"W2123428158","doi":"10.1093/nar/gkq1031","title":"A prominent  -hairpin structure in the winged-helix domain of RECQ1 is required for DNA unwinding and oligomer formation","year":2010,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Associazione Italiana per la Ricerca sul Cancro; Stiftelsen för Strategisk Forskning; Ontario Genomics Institute; Ontario Genomics; Genome Canada; Ontario Innovation Trust; Wellcome Trust; GlaxoSmithKline","keywords":"Biology; Oligomer; Helix (gastropod); DNA; Domain (mathematical analysis); Genetics; Base sequence; Biophysics; Evolutionary biology; Zoology; Physics; Gastropoda","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001553279,0.0001013304,0.0001208064,0.0001241018,0.0001199877,0.00003862998,0.0003174198,0.0002107995,0.00002366714],"category_scores_gemma":[0.0002975812,0.00007565157,0.000047741,0.0001874593,0.0001392605,0.00001372992,0.0001530149,0.0002664961,0.000001673939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001803227,"about_ca_system_score_gemma":0.00005677344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001230695,"about_ca_topic_score_gemma":0.00008293974,"domain_scores_codex":[0.9987224,0.0001372947,0.0002138299,0.0002663594,0.0003334682,0.0003265947],"domain_scores_gemma":[0.9992921,0.00004573416,0.0000579258,0.0004124433,0.0001425814,0.00004923114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001244127,0.00002082649,0.0004231866,0.00007650263,0.00001119038,9.645563e-7,0.001401358,3.269782e-7,0.9931674,0.0007081668,0.001064917,0.003000723],"study_design_scores_gemma":[0.0008062791,0.0004410794,0.001656856,0.00002893573,0.000004600026,0.00001961496,0.001202333,0.0002662636,0.9776298,0.004091505,0.01374607,0.000106678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997674,0.00007344526,0.0002057349,0.0007946896,0.00005815348,0.0007978358,0.0000378413,0.00000541493,0.0003528221],"genre_scores_gemma":[0.9953415,0.00002896916,0.004179972,0.00008382896,0.0001146322,0.00007544681,0.00003727604,0.00002005001,0.0001182722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01553764,"threshold_uncertainty_score":0.3084982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02800876555490463,"score_gpt":0.3270277602569915,"score_spread":0.2990189947020869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}