{"id":"W2123431118","doi":"10.1038/ki.2014.48","title":"Genetic testing for nephrotic syndrome and FSGS in the era of next-generation sequencing","year":2014,"lang":"en","type":"review","venue":"Kidney International","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Nephrotic syndrome; Medicine; Focal segmental glomerulosclerosis; Biology; Computational biology; Internal medicine; Glomerulonephritis; Kidney","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025776,0.0001635562,0.0005471456,0.0001358293,0.00003237004,0.00004361288,0.0001317766,0.00008499796,0.00002788631],"category_scores_gemma":[0.001352322,0.000107185,0.0001660049,0.0001237615,0.00004412199,0.00004929257,0.00002725496,0.0001774458,0.00000388866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008322881,"about_ca_system_score_gemma":0.0003869957,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004770421,"about_ca_topic_score_gemma":0.000003475277,"domain_scores_codex":[0.9988948,0.00006205319,0.0004776379,0.0002095076,0.000242022,0.0001140142],"domain_scores_gemma":[0.9991474,0.0002755894,0.0002350388,0.0001453311,0.0001179264,0.00007870685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001478116,0.00008120271,0.0008010598,0.03176387,0.0003077475,0.00007777481,0.0002114669,0.00001486584,0.0001555852,0.0008466138,0.002263153,0.9634619],"study_design_scores_gemma":[0.00157357,0.0007294325,0.005654831,0.07198112,0.002299248,0.003626547,0.0000896964,0.01457186,0.000005306837,0.0006468374,0.8982778,0.000543709],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003159127,0.9940763,0.0002842752,0.0005472836,0.0003033493,0.00109326,0.0001535727,0.00001100311,0.0003718872],"genre_scores_gemma":[0.01244856,0.9802195,0.004603565,0.0008977567,0.0007896403,0.0002886458,0.0006087834,0.00003617354,0.0001073186],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9629182,"threshold_uncertainty_score":0.4370879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1054245189743959,"score_gpt":0.3360797841475763,"score_spread":0.2306552651731804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}